Benzamide, N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3, 4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-

Base Information

Chemical Name:Benzamide, N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3, 4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-
CAS No.:873091-39-5
Molecular Formula:C22H21F2N7O4S
Molecular Weight:517.516
Hs Code.:

Benzamide,
N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3,
4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3, 4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-

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Technology Process of Benzamide, N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3, 4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-

There total 1 articles about Benzamide, N-cyclopropyl-2,4-difluoro-5-[[5-(1-methylethyl)-6-[5-(methylsulfonyl)-1,3, 4-oxadiazol-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: C₂₂H₂₁F₂N₇O₂S

: 873091-39-5
C₂₂H₂₁F₂N₇O₄S

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2008.01.012

Reference yield: 67.0%

: 873091-39-5
C₂₂H₂₁F₂N₇O₄S

: 40499-83-0,83220-72-8,100243-39-8,2799-21-5
(3R)-pyrrolidinol

: N-cyclopropyl-2,4-difluoro-5-(5-isopropyl-6-(5-((R)-pyrrolidin-3-yloxy)-1,3,4-oxadiazol-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)benzamide

Guidance literature:: (3R)-pyrrolidinol; With sodium hydride; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 0 ℃; for 0.25h;

C₂₂H₂₁F₂N₇O₄S; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 0 ℃; for 1h;