N,N'-(2-Chloro-1,4-phenylene)bisacetamide

Base Information

• Chemical Name: N,N'-(2-Chloro-1,4-phenylene)bisacetamide
• CAS No.: 50610-32-7
• Molecular Formula: C10H11 Cl N2 O2
• Molecular Weight: 226.663
• Hs Code.: 2924299090
• European Community (EC) Number: 256-653-9
• DSSTox Substance ID: DTXSID30198661
• Nikkaji Number: J261.557F
• Wikidata: Q83071486
• Mol file: 50610-32-7.mol

Synonyms:50610-32-7;N,N'-(2-Chloro-1,4-phenylene)diacetamide;N,N'-(2-Chloro-1,4-phenylene)bisacetamide;N-(4-acetamido-3-chlorophenyl)acetamide;EINECS 256-653-9;SCHEMBL3786387;DTXSID30198661;MFCD00221890;AKOS001463031;DS-5016;SB80145;CS-0153978;NS00032096;C75371;A871506;N-(4-ACETYLAMINO-3-CHLORO-PHENYL)-ACETAMIDE;Z228262406;N pound notN'-(2-Chloro-1 pound not4-phenylene)diacetamide

Chemical Property of N,N'-(2-Chloro-1,4-phenylene)bisacetamide

Chemical Property:

• Boiling Point: 485.8oC at 760 mmHg
• Flash Point: 247.6oC
• PSA: 58.20000
• Density: 1.352g/cm3
• LogP: 2.40280
• Storage Temp.: 2-8°C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 226.0509053
• Heavy Atom Count: 15
• Complexity: 258

Purity/Quality:

99% ^*data from raw suppliers

N,N'-(2-Chloro-1,4-phenylene)diacetamide 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC(=C(C=C1)NC(=O)C)Cl

Technology Process of N,N'-(2-Chloro-1,4-phenylene)bisacetamide

There total 4 articles about N,N'-(2-Chloro-1,4-phenylene)bisacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-p-phenylenediamine sulfate (61702-44-1,6219-71-2) → N,N'-(chloro-p-phenylene)-bis-acetamide (50610-32-7)

Guidance literature:

With acetic anhydride; acetic acid; In water;

Reference yield:

N,N'-cyclohexa-2,5-diene-1,4-diylidene-bis-acetamide (342412-89-9) → N,N'-(chloro-p-phenylene)-bis-acetamide (50610-32-7)

Guidance literature:

With hydrogenchloride; water; acetic acid;

DOI:10.1021/ja01167a098

Reference yield:

N,N'-diacetyl-1,4-phenylenediamine (140-50-1) → N,N'-(chloro-p-phenylene)-bis-acetamide (50610-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: lead (IV)-acetate

2: acetic acid; water; HCl

With lead(IV) acetate; hydrogenchloride; water; acetic acid;

DOI:10.1021/ja01167a098

upstream raw materials:

N,N'-cyclohexa-2,5-diene-1,4-diylidene-bis-acetamide

acetic anhydride

N,N'-diacetyl-1,4-phenylenediamine

2-chloro-p-phenylenediamine sulfate

Downstream raw materials:

1-amino-2-nitro-5-chloro-4-aminobenzene

Refernces