1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene

Base Information

Chemical Name:1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene
CAS No.:873373-81-0
Molecular Formula:C8H7BrF2O
Molecular Weight:237.04100
Hs Code.:
DSSTox Substance ID:DTXSID70395374
Wikidata:Q82195436

Synonyms:1-(bromomethyl)-2,5-difluoro-4-methoxybenzene;873373-81-0;SCHEMBL3775780;DTXSID70395374;QDZHHAGHCLWYBZ-UHFFFAOYSA-N;2,5-Difluoro-4-methoxybenzyl bromide

Suppliers and Price of 1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2,5-Difluoro-4-methoxybenzylbromide
1g
$ 1564.50

Alichem
2,5-Difluoro-4-methoxybenzylbromide
500mg
$ 831.30

Alichem
2,5-Difluoro-4-methoxybenzylbromide
250mg
$ 480.00

Total 0 raw suppliers

Chemical Property of 1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene

Chemical Property:

PSA：9.23000
LogP:2.86830
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:235.96483
Heavy Atom Count:12
Complexity:145

Purity/Quality:: 2,5-Difluoro-4-methoxybenzylbromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)F)CBr)F

Technology Process of 1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene

There total 3 articles about 1-(Bromomethyl)-2,5-difluoro-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 922719-76-4
(2,5-difluoro-4-methoxyphenyl)methanol

: 873373-81-0
1-(bromomethyl)-2,5-difluoro-4-methoxybenzene

Guidance literature:: With pyridine; sulfurous dibromide; In dichloromethane; Inert atmosphere; Reflux;

Reference yield:

: 879093-08-0
2,5-difluoro-4-methoxybenzaldehyde

: 873373-81-0
1-(bromomethyl)-2,5-difluoro-4-methoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C / Inert atmosphere

2: pyridine; sulfurous dibromide / dichloromethane / Inert atmosphere; Reflux

With pyridine; sodium tetrahydroborate; sulfurous dibromide; In methanol; dichloromethane;