1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-

Base Information

Chemical Name:1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-
CAS No.:873913-85-0
Molecular Formula:C22H17BrN2
Molecular Weight:389.28800
Hs Code.:
DSSTox Substance ID:DTXSID40469197

Synonyms:1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-;873913-85-0;DTXSID40469197

Suppliers and Price of 1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-

Chemical Property:

PSA：17.82000
LogP:6.02790
XLogP3:6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:388.05751
Heavy Atom Count:25
Complexity:397

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C(=C(N=C2Br)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)-

There total 1 articles about 1H-Imidazole, 2-bromo-4,5-diphenyl-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 7346-22-7
1-benzyl-4,5-diphenyl-1H-imidazole

: 873913-85-0
1-benzyl-2-bromo-4,5-diphenylimidazole

Guidance literature:: With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 4h;
DOI:10.1002/jhet.5570420717

Reference yield: 43.0%

: 873913-85-0
1-benzyl-2-bromo-4,5-diphenylimidazole

: 7223-38-3
N,N-Dimethylpropargylamin

: 873913-97-4
[3-(1-benzyl-4,5-diphenyl-imidazol-2-yl)-prop-2-ynyl]-dimethyl-amine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; TEA; at 80 ℃; for 24h;
DOI:10.1002/jhet.5570420717

Reference yield:

: 873913-85-0
1-benzyl-2-bromo-4,5-diphenylimidazole

: [3-(1-benzyl-4,5-diphenyl-imidazol-2-yl)-propyl]-dimethyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / Pd(PPh₃)2Cl₂; CuI; TEA / 24 h / 80 °C

2: 63 percent / H₂ / 10 percent Pd/C / ethanol / 16 h / 20 °C / 760 Torr

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; TEA; hydrogen; palladium on activated charcoal; In ethanol; 1: Sonogashira coupling;
DOI:10.1002/jhet.5570420717