6-Chloro-N-(2-pyridinylmethyl)-2-pyrazinamine

Base Information

• Chemical Name: 6-Chloro-N-(2-pyridinylmethyl)-2-pyrazinamine
• CAS No.: 874143-67-6
• Molecular Formula: C₁₀H₉ClN₄
• Molecular Weight: 220.661
• Mol file: 874143-67-6.mol

Synonyms:

Chemical Property of 6-Chloro-N-(2-pyridinylmethyl)-2-pyrazinamine

Chemical Property:

• Melting Point: 107-108.5 °C
• Boiling Point: 371.6±37.0 °C(Predicted)
• PKA: 4.34±0.12(Predicted)
• PSA: 50.70000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 2.21010

Purity/Quality:

98%min ^*data from raw suppliers

6-CHLORO-N-(2-PYRIDINYLMETHYL)-2-PYRAZINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Chloro-N-(2-pyridinylmethyl)-2-pyrazinamine

There total 1 articles about 6-Chloro-N-(2-pyridinylmethyl)-2-pyrazinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.7%

2-(Aminomethyl)pyridine (3731-51-9) + 2,6-dichloropyrazine (4774-14-5) → 2-(2-pyridylmethylamino)-6-chloropyrazine (874143-67-6)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 18h;

DOI:10.1021/jm050983g

upstream raw materials:

2-(Aminomethyl)pyridine

2,6-dichloropyrazine