2-Acetamido-5-phenylpentanoic acid

Base Information

Chemical Name:2-Acetamido-5-phenylpentanoic acid
CAS No.:5440-44-8
Molecular Formula:C₁₃H₁₇NO₃
Molecular Weight:235.283
Hs Code.:
NSC Number:20167
DSSTox Substance ID:DTXSID60281111
Mol file:5440-44-8.mol

Synonyms:2-acetamido-5-phenylpentanoic acid;n-acetyl-5-phenylnorvaline;108019-30-3;5440-44-8;NSC20167;starbld0023044;SCHEMBL5505937;DTXSID60281111;NATYAPACRIEJOH-UHFFFAOYSA-N;NSC-20167;AKOS013464837;CS-0344319;FT-0765262;(+/-)-2-(acetylamino)-5-phenyl-pentanoic acid;EN300-1217904;F2147-6637

Suppliers and Price of 2-Acetamido-5-phenylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Acetamido-5-phenylpentanoic acid

Chemical Property:

Vapor Pressure:4.45E-11mmHg at 25°C
Boiling Point:506.4°Cat760mmHg
Flash Point:260.1°C
PSA：66.40000
Density:1.143g/cm³
LogP:1.98950
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:235.12084340
Heavy Atom Count:17
Complexity:259

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CCCC1=CC=CC=C1)C(=O)O

Technology Process of 2-Acetamido-5-phenylpentanoic acid

There total 10 articles about 2-Acetamido-5-phenylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 52161-73-6
2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester

: 108019-30-3,5440-44-8
DL-N-acetyl-2-amino-5-phenylpentanoic acid

Guidance literature:: 2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester; With sodium hydroxide; In water; at 100 ℃; for 3h;

With hydrogenchloride; In water; at 5 - 100 ℃; for 1h; pH=1.0 - 5.0;

Reference yield: 43.0%

: 108019-30-3,5440-44-8
DL-N-acetyl-2-amino-5-phenylpentanoic acid

: 62777-26-8,5440-44-8
D-N-acetyl-2-amino-5-phenylpentanoic acid

Guidance literature:: With potassium hydroxide; cobalt(II) chloride; Acylase I; In water; at 40 ℃; for 24h; pH=8; Enzymatic reaction;

Reference yield:

: 637-59-2
1-Bromo-3-phenylpropane

: 62777-26-8,5440-44-8
D-N-acetyl-2-amino-5-phenylpentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium ethoxide / ethanol / 1.5 h / 20 °C

1.2: 98 percent / ethanol / 16 h / Heating

2.1: NaOH / 3 h / 100 °C

3.1: 68.9 g / CoCl₂; KCl; KOH / acylase I from Aspergillus melleus / H₂O / 24 h / 40 °C / pH 8.0

With potassium hydroxide; sodium hydroxide; potassium chloride; sodium ethanolate; acylase I from Aspergillus melleus; In ethanol; water;
DOI:10.1016/j.bmc.2005.07.070