N,N-dimethylethylenediamine hydrochloride

Base Information

• Chemical Name: N,N-dimethylethylenediamine hydrochloride
• CAS No.: 3984-76-7
• Molecular Formula: C4H12 N2 . 2 Cl H
• Molecular Weight: 161.075
• Mol file: 3984-76-7.mol

Synonyms:N1,N1-Dimethylethane-1,2-diamine hydrochloride;69981-61-9;SCHEMBL1533611;GFMUAWWLXMJVRV-UHFFFAOYSA-N;dimethylaminoethylamine hydrochloride;N,N-dimethylethylenediamine hydrochloride

Chemical Property of N,N-dimethylethylenediamine hydrochloride

Chemical Property:

• Vapor Pressure: 49.3mmHg at 25°C
• Boiling Point: 93.5°Cat760mmHg
• Flash Point: 23.9°C
• PSA: 29.26000
• Density: g/cm³
• LogP: 1.81100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 124.0767261
• Heavy Atom Count: 7
• Complexity: 26.7

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCN.Cl
• Uses: N,N-Dimethylethylenediamine Dihydrochloride is a useful reagent for studying cytotoxic activity of cis-?[APtCl2] complexes. It is a versatile ethylenediamine derivative used as an intermediate in the organic synthesis of neurochemicals, antitumor agents and other pharmaceutical compounds.

Technology Process of N,N-dimethylethylenediamine hydrochloride

There total 2 articles about N,N-dimethylethylenediamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2-dimethylamino-ethyl)-carbamic acid benzyl ester → N1,N1-dimethylethane-1,2-diamine dihydrochloride (3984-76-7)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; water; for 5h; under 5171.62 Torr;

Reference yield: 91.0%

N,N-Dimethyl-2-nitroethylenamin (82781-92-8) → N1,N1-dimethylethane-1,2-diamine dihydrochloride (3984-76-7)

Guidance literature:

N,N-Dimethyl-2-nitroethylenamin; With C₃₆H₅₆Cl₃CrN₂O; magnesium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere; Schlenk technique;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate; at 20 ℃;

DOI:10.1021/jacs.0c12318

Reference yield: 97.0%

C17H24N2O7 + N1,N1-dimethylethane-1,2-diamine dihydrochloride (3984-76-7) → C21H34N4O6

Guidance literature:

With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.66667h;

upstream raw materials:

N,N-Dimethyl-2-nitroethylenamin