N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide

Base Information

Chemical Name:N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide
CAS No.:874813-22-6
Molecular Formula:C₁₄H₁₂F₃NO₂S
Molecular Weight:315.316
Hs Code.:
European Community (EC) Number:830-957-7
Nikkaji Number:J3.483.760K

Synonyms:N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide;N-(4-(Trifluoromethyl)benzyl)benzenesulfonamide;N-(4-Trifluoromethyl-benzyl)-benzenesulfonamide;874813-22-6;SCHEMBL3853891;AKOS009084153;Z165202978

Suppliers and Price of N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:315.05408429
Heavy Atom Count:21
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)NCC2=CC=C(C=C2)C(F)(F)F

Technology Process of N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide

There total 1 articles about N-[4-(Trifluoromethyl)benzyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 874813-22-6
N-(4-Trifluoromethyl-benzyl)-benzenesulfonamide

Guidance literature:

Reference yield:

: 874813-22-6
N-(4-Trifluoromethyl-benzyl)-benzenesulfonamide

: 1325235-13-9
N-[1-(4-Trifluoromethyl-phenyl)-meth-(E)-ylidene]-benzenesulfonamide

Guidance literature:: N-(4-Trifluoromethyl-benzyl)-benzenesulfonamide; With tert-butylhypochlorite; sodium sulfate; potassium bromide; In acetonitrile; at 0 ℃; for 1h;

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In acetonitrile; at 0 ℃; for 0.5h;

With sodium carbonate; In acetonitrile; at 0 ℃; for 7h;
DOI:10.1002/anie.201607223

Reference yield:

: 874813-22-6
N-(4-Trifluoromethyl-benzyl)-benzenesulfonamide

: N-(cyano(4-(trifluoromethyl)phenyl)methyl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium bromide; sodium sulfate; tert-butylhypochlorite / acetonitrile / 1 h / 0 °C

1.2: 0.5 h / 0 °C

1.3: 7 h / 0 °C

2.1: lithium perchlorate / acetonitrile / 20 °C

With tert-butylhypochlorite; lithium perchlorate; sodium sulfate; potassium bromide; In acetonitrile;
DOI:10.1002/anie.201607223