Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-

Base Information

Chemical Name:Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-
CAS No.:874906-91-9
Molecular Formula:C27H23N3
Molecular Weight:389.5
Hs Code.:
DSSTox Substance ID:DTXSID70470993
Nikkaji Number:J2.490.227G

Synonyms:Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-;874906-91-9;DTXSID70470993

Suppliers and Price of Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:389.189197746
Heavy Atom Count:30
Complexity:466

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CN2)C3=CC(=CN=C3)C(C4=CC=CC=C4)C5=CC=CN5

Technology Process of Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)-

There total 8 articles about Pyridine, 3,5-bis(phenyl-1H-pyrrol-2-ylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 109-97-7,30604-81-0
pyrrole

: 234111-11-6
α,α'-diphenyl-3,5-pyridinedimethanol

: 874906-91-9
3,5-bis[phenyl(2-pyrrolyl)methyl]pyridine

Guidance literature:: α,α'-diphenyl-3,5-pyridinedimethanol; With methanesulfonyl chloride; triethylamine; In chloroform; for 72h; cooling;

pyrrole; for 72h;
DOI:10.1002/ejoc.200500496

Reference yield:

: 499-81-0
3,5-Pyridinedicarboxylic acid

: 874906-91-9
3,5-bis[phenyl(2-pyrrolyl)methyl]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: thionyl chloride / dimethylformamide

2: aluminum chloride

3: sodium borohydride / ethanol

4: triethylamine / CH₂Cl₂ / 0 °C

5: 20 °C

With sodium tetrahydroborate; aluminium trichloride; thionyl chloride; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide; 2: Friedel-Crafts acylation;
DOI:10.1021/ol071052x

Reference yield:

: 15074-61-0
pyridine-3,5-dicarbonyl dichloride

: 874906-91-9
3,5-bis[phenyl(2-pyrrolyl)methyl]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: aluminum chloride

2: sodium borohydride / ethanol

3: triethylamine / CH₂Cl₂ / 0 °C

4: 20 °C

With sodium tetrahydroborate; aluminium trichloride; triethylamine; In ethanol; dichloromethane; 1: Friedel-Crafts acylation;
DOI:10.1021/ol071052x