5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate

Base Information

• Chemical Name: 5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate
• CAS No.: 99304-35-5
• Molecular Formula: C₁₆H₁₈BrNO₄
• Molecular Weight: 368.227
• Mol file: 99304-35-5.mol

Synonyms:5-Bromo-N,O-dibutyryldioxindole;BUTANOIC ACID,5-BROMO-2,3-DIHYDRO-2-OXO-1-(1-OXOBUTYL)-1H-INDOL-3-YL ESTER;5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate;

Chemical Property of 5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate

Chemical Property:

• Vapor Pressure: 3.71E-10mmHg at 25°C
• Boiling Point: 500.7°Cat760mmHg
• Flash Point: 256.6°C
• PSA: 63.68000
• Density: 1.46g/cm³
• LogP: 3.57180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate

There total 2 articles about 5-bromo-1-butanoyl-2-oxo-2,3-dihydro-1H-indol-3-yl butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-3-hydroxyindolin-2-one (99304-37-7) + butyryl chloride (141-75-3) → 5-Bromo-N,O-dibutyryldioxindole (99304-35-5)

Guidance literature:

With pyridine; at 50 - 70 ℃; for 0.416667h;

DOI:10.1007/BF00767830

Reference yield:

butanoic acid anhydride (106-31-0) + 5-bromo-3-hydroxyindolin-2-one (99304-37-7) → 5-Bromo-N,O-dibutyryldioxindole (99304-35-5)

Guidance literature:

at 135 ℃; for 10h;

DOI:10.1007/BF00767830

upstream raw materials:

butanoic acid anhydride

5-bromo-3-hydroxyindolin-2-one

butyryl chloride