(4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one

Base Information

Chemical Name:(4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one
CAS No.:87519-67-3
Molecular Formula:C₁₆H₁₅NOS
Molecular Weight:269.367
Hs Code.:
DSSTox Substance ID:DTXSID70527259
Wikidata:Q82396394

Synonyms:87519-67-3;DTXSID70527259;(4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one

Suppliers and Price of (4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:269.08743528
Heavy Atom Count:19
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(=O)N2C1C3=C(C(C2)C4=CC=CC=C4)SC=C3
Isomeric SMILES:C1CC(=O)N2[C@H]1C3=C([C@@H](C2)C4=CC=CC=C4)SC=C3

Technology Process of (4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one

There total 4 articles about (4R,9aR)-4-Phenyl-4,8,9,9a-tetrahydrothieno[2,3-g]indolizin-7(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87520-01-2
2-<2-(2,5-dioxopyrrolidin-1-yl)-1-phenylethyl>thiophen

: 87519-67-3
4,5,9,9aα-tetrahydro-4β-phenylthieno<2,3-g>indolizin-7(8H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄, CH₃SO₃H

2: ethereal HCl / ethanol

With hydrogenchloride; sodium tetrahydroborate; methanesulfonic acid; In ethanol;
DOI:10.1021/jo00173a053

Reference yield:

: 7568-93-6,1936-63-6
2-Amino-1-phenylethanol

: 87519-67-3
4,5,9,9aα-tetrahydro-4β-phenylthieno<2,3-g>indolizin-7(8H)-one

Guidance literature:: Multi-step reaction with 3 steps

2: NaBH₄, CH₃SO₃H

3: ethereal HCl / ethanol

With hydrogenchloride; sodium tetrahydroborate; methanesulfonic acid; In ethanol;
DOI:10.1021/jo00173a053