N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide

Base Information

• Chemical Name: N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide
• CAS No.: 92982-43-9
• Molecular Formula: C12H10N2O3
• Molecular Weight: 230.223
• DSSTox Substance ID: DTXSID90700446
• Mol file: 92982-43-9.mol

Synonyms:92982-43-9;DTXSID90700446;N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide

Chemical Property of N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide

Chemical Property:

• Boiling Point: 357.7°Cat760mmHg
• Flash Point: 170.1°C
• Density: 1.381g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 230.06914219
• Heavy Atom Count: 17
• Complexity: 424

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN(C(=O)C2=CC=CO2)N)C(=O)C=C1

Technology Process of N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide

There total 6 articles about N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]furan-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.7%

2-furoic acid hydrazide (3326-71-4) + salicylaldehyde (90-02-8) → N'‐(2‐hydroxybenzylidene)furan‐2‐carbohydrazide (92982-43-9)

Guidance literature:

In ethanol; at 80 ℃; for 2h;

DOI:10.1002/aoc.5116

Reference yield: 80.0%

2-furoic acid hydrazide (3326-71-4) + salicylaldehyde (90-02-8) → (E)-N’-(2-hydroxybenzylidene)furan-2-carbohydrazone (92982-43-9)

Guidance literature:

In ethanol; for 0.5h; Heating;

Reference yield:

2-furoic acid hydrazide (3326-71-4) + 2-methyl-benzyl alcohol (89-95-2) → (E)-N’-(2-hydroxybenzylidene)furan-2-carbohydrazone (92982-43-9)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2005.09.058

upstream raw materials:

2-furoic acid hydrazide

salicylaldehyde

2-methyl-benzyl alcohol

2-furanoic acid