20-Hydroxy-20-methylpregn-4-en-3-one

Base Information

• Chemical Name: 20-Hydroxy-20-methylpregn-4-en-3-one
• CAS No.: 20917-51-5
• Molecular Formula: C₂₂H₃₄O₂
• Molecular Weight: 330.511
• NSC Number: 125050
• DSSTox Substance ID: DTXSID70943177
• Mol file: 20917-51-5.mol

Synonyms:20917-51-5;20-hydroxy-20-methylpregn-4-en-3-one;NSC125050;DTXSID70943177;NSC-125050

Chemical Property of 20-Hydroxy-20-methylpregn-4-en-3-one

Chemical Property:

• Vapor Pressure: 2.51E-10mmHg at 25°C
• Boiling Point: 458.3°Cat760mmHg
• Flash Point: 195.1°C
• Density: 1.08g/cm³
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 330.255880323
• Heavy Atom Count: 24
• Complexity: 589

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2C(C)(C)O)CCC4=CC(=O)CCC34C

Technology Process of 20-Hydroxy-20-methylpregn-4-en-3-one

There total 3 articles about 20-Hydroxy-20-methylpregn-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β,20-dihydroxy-20-methylpregn-5-ene (20976-92-5) → 20-hydroxy-20-methylpregn-4-en-3-one (20917-51-5)

Guidance literature:

With cyclohexanone; aluminum isopropoxide; toluene;

DOI:10.1021/jo01106a037

Reference yield:

→ 20-hydroxy-20-methylpregn-4-en-3-one (20917-51-5)

Guidance literature:

Herstellung von 20-Hydroxy-23,24-dinor-<4-¹⁴C>chol-4-en-3-on;

DOI:10.1021/jo01106a037

Reference yield:

→ 17-(1-Hydroxy-1-methyl-ethyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one (20917-51-5)

Guidance literature:

aus Progesteron;

upstream raw materials:

3β,20-dihydroxy-20-methylpregn-5-ene