N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea

Base Information

Chemical Name:N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea
CAS No.:87653-25-6
Molecular Formula:C₁₈H₂₄N₄O₂
Molecular Weight:328.414
Hs Code.:
DSSTox Substance ID:DTXSID20539983
Wikidata:Q82415828

Synonyms:87653-25-6;DTXSID20539983;N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea

Suppliers and Price of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:328.18992602
Heavy Atom Count:24
Complexity:493

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NC(=O)NCCCCN1C(=O)C=CC(=N1)C2=CC=CC=C2

Technology Process of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea

There total 3 articles about N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-propan-2-ylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 79460-62-1
2-(2-aminobutyl)-6-phenyl-3(2H)-pyridazinone

: 1795-48-8
Isopropyl isocyanate

: 87653-25-6
1-Isopropyl-3-[4-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-butyl]-urea

Guidance literature:: In chloroform;

Reference yield:

: 2166-31-6
6-phenylpyridazin-3(2H)-one

: 87653-25-6
1-Isopropyl-3-[4-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-butyl]-urea

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / tetra-n-butylammonium bromide, potassium hydroxyde / benzene / 6 h / Ambient temperature

2: 87 percent / 1.) 100percent hydrazine hydrate; 2.) aq. 10percent hydrochloric / ethanol / 1.) reflux, 5 h; 2.) pH=4.0, reflux, 2 h

3: 61 percent / CHCl₃

With hydrogenchloride; potassium hydroxide; tetrabutylammomium bromide; hydrazine hydrate; In ethanol; chloroform; benzene;

Reference yield:

: 79222-75-6
6-phenyl-2-<2-(phthalimido)butyl>-3(2H)-pyridazinone

: 87653-25-6
1-Isopropyl-3-[4-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-butyl]-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / 1.) 100percent hydrazine hydrate; 2.) aq. 10percent hydrochloric / ethanol / 1.) reflux, 5 h; 2.) pH=4.0, reflux, 2 h

2: 61 percent / CHCl₃

With hydrogenchloride; hydrazine hydrate; In ethanol; chloroform;