N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea

Base Information

Chemical Name:N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea
CAS No.:87653-30-3
Molecular Formula:C₂₁H₂₂N₄O₂
Molecular Weight:362.431
Hs Code.:
DSSTox Substance ID:DTXSID00539986
Wikidata:Q82415833

Synonyms:87653-30-3;DTXSID00539986;N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea

Suppliers and Price of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea

Chemical Property:

Melting Point:121-123 °C(Solv: acetonitrile (75-05-8))
PSA：79.51000
Density:1.19±0.1 g/cm3(Predicted)
LogP:3.78960
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:362.17427596
Heavy Atom Count:27
Complexity:561

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=O)C=C2)CCCCNC(=O)NC3=CC=CC=C3

Technology Process of N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea

There total 3 articles about N-[4-(6-Oxo-3-phenylpyridazin-1(6H)-yl)butyl]-N'-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 103-71-9
phenyl isocyanate

: 79460-62-1
2-(2-aminobutyl)-6-phenyl-3(2H)-pyridazinone

: 87653-30-3
6-phenyl-2-<4-(3-phenyl-1-ureido)butyl>-3(2H)-pyridazinone

Guidance literature:: In chloroform; for 2h; Heating;

Reference yield:

: 2166-31-6
6-phenylpyridazin-3(2H)-one

: 87653-30-3
6-phenyl-2-<4-(3-phenyl-1-ureido)butyl>-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / tetra-n-butylammonium bromide, potassium hydroxyde / benzene / 6 h / Ambient temperature

2: 87 percent / 1.) 100percent hydrazine hydrate; 2.) aq. 10percent hydrochloric / ethanol / 1.) reflux, 5 h; 2.) pH=4.0, reflux, 2 h

3: 90 percent / CHCl₃ / 2 h / Heating

With hydrogenchloride; potassium hydroxide; tetrabutylammomium bromide; hydrazine hydrate; In ethanol; chloroform; benzene;

Reference yield:

: 79222-75-6
6-phenyl-2-<2-(phthalimido)butyl>-3(2H)-pyridazinone

: 87653-30-3
6-phenyl-2-<4-(3-phenyl-1-ureido)butyl>-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / 1.) 100percent hydrazine hydrate; 2.) aq. 10percent hydrochloric / ethanol / 1.) reflux, 5 h; 2.) pH=4.0, reflux, 2 h

2: 90 percent / CHCl₃ / 2 h / Heating

With hydrogenchloride; hydrazine hydrate; In ethanol; chloroform;