2-Amino-3-nitrobiphenyl

Base Information

Chemical Name:2-Amino-3-nitrobiphenyl
CAS No.:87666-60-2
Molecular Formula:C12H10N2O2
Molecular Weight:214.224
Hs Code.:
DSSTox Substance ID:DTXSID20522299
Nikkaji Number:J36.334K
Wikidata:Q82387448

Synonyms:2-amino-3-nitrobiphenyl;87666-60-2;2-amino-3 -nitrobiphenyl;SCHEMBL1251652;DTXSID20522299;YNUSHIPXRLCOCK-UHFFFAOYSA-N;3-Nitro[1,1'-biphenyl]-2-amine

Suppliers and Price of 2-Amino-3-nitrobiphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Amino-3-nitrobiphenyl

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:214.074227566
Heavy Atom Count:16
Complexity:246

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=CC=C2)[N+](=O)[O-])N

Technology Process of 2-Amino-3-nitrobiphenyl

There total 1 articles about 2-Amino-3-nitrobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15813-12-4
6-methyl-4-nitro-5,6-dihydro-dibenzo[1,2]azaborinine

: 87666-60-2
3-nitro-[1,1'-biphenyl]-2-amine

: 11113-50-1,14635-83-7
boric acid

Guidance literature:: In sulfuric acid;
DOI:10.1016/S0040-4020(01)93188-6

Reference yield:

: 87666-60-2
3-nitro-[1,1'-biphenyl]-2-amine

: 84-15-1
o-terphenyl

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) sodium nitrite, concentrated sulfuric acid; 2.) potassium iodide / 1.) water, 0-5 deg C, 2.5 h; 2.) water

2: 41 percent / copper powder / Heating

3: 84 percent / activated iron, hydrogen chloride / benzene

4: 1.) natrium nitrite, concentrated sulfuric acid; 2.) potassium iodide

5: 0.416 g / copper powder / 3 h / 260 - 270 °C

With hydrogenchloride; sulfuric acid; iron; copper; potassium iodide; sodium nitrite; In benzene;

Reference yield:

: 87666-60-2
3-nitro-[1,1'-biphenyl]-2-amine

: 4-(4-methoxybenzyl)-5a-methyl-5a,6-dihydronaphtho[3,2,1-cd]indol-5(4H)-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium nitrite; sulfuric acid; acetic acid / 0.25 h / 15 °C

1.2: 20 °C

2.1: iron; ammonium chloride / ethanol; water / Heating

3.1: triethylamine / dichloromethane / 1 h / 0 °C

4.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

4.2: 2 h / 0 - 20 °C / Inert atmosphere

5.1: sodium carbonate; palladium diacetate / N,N-dimethyl-formamide / 4 h / 95 °C / Schlenk technique; Inert atmosphere; Sealed tube

With sulfuric acid; palladium diacetate; iron; sodium hydride; sodium carbonate; ammonium chloride; acetic acid; triethylamine; sodium nitrite; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.7b03843