2,2,4-Trimethylquinolin-6-one

Base Information

• Chemical Name: 2,2,4-Trimethylquinolin-6-one
• CAS No.: 4071-18-5
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID50193693
• Nikkaji Number: J132.134J
• Wikidata: Q83066433
• Mol file: 4071-18-5.mol

Synonyms:4071-18-5;2,2,4-trimethylquinolin-6-one;2,6-Dihydro-2,2,4-trimethyl-6-quinolone;2,2,4-Trimethyl-6(2H)-quinolone;6(2H)-Quinolone, 2,2,4-trimethyl-;Ethoxyquin quinone imine;2,2,4-trimethyl-6-oxo-2,6-dihydroquinoline;SCHEMBL9760161;DTXSID50193693;AKOS015868318;6(2H)-Quinolinone, 2,2,4-trimethyl-;AS-82779;FT-0667067;D86178;2,6-Dihydro-2,2,4-trimethyl-6-quinolone, analytical standard

Chemical Property of 2,2,4-Trimethylquinolin-6-one

Chemical Property:

• Vapor Pressure: 0.00267mmHg at 25°C
• Melting Point: 43-45oC
• Boiling Point: 286.2°Cat760mmHg
• Flash Point: 115.7°C
• PSA: 29.43000
• Density: 1.07g/cm³
• LogP: 1.66680
• Storage Temp.: Amber Vial, Refrigerator, Under Inert Atmosphere
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 187.099714038
• Heavy Atom Count: 14
• Complexity: 420

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dihydro-2,2,4-trimethyl-6-quinolone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(N=C2C1=CC(=O)C=C2)(C)C
• Uses: A metabolite of Ethoxyquin. An oxidation product of the antidegradant Ethoxyquin found in the muscle of Atlantic salmon

Technology Process of 2,2,4-Trimethylquinolin-6-one

There total 4 articles about 2,2,4-Trimethylquinolin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2,2,4-trimethyl-6-hydroxy-1,2-dihydroquinoline (72107-05-2) → 2,2,4-trimethyl-6-oxo-2,6-dihydroquinoline (4071-18-5)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; epichlorohydrin; In water; benzene; at 50 - 60 ℃; for 1h;

DOI:10.1023/A:1016367000262

Reference yield:

2,2,4-trimethyl-6-hydroxy-1,2-dihydroquinoline (72107-05-2) + N,N'-diphenyl-1,4-phenylenediamine (6246-98-6,73334-88-0,73334-89-1) → 2,2,4-trimethyl-6-oxo-2,6-dihydroquinoline (4071-18-5) + N,N'-diphenyl-1,4-phenylenediamine (74-31-7,943443-44-5)

Guidance literature:

In chlorobenzene; at 23 ℃; Rate constant; Kinetics; other temps.;

DOI:10.1007/BF00869525

Reference yield:

2,2,4-trimethyl-6-ethoxy-1,2-dihydroquinoline (3763-77-7) → 2,2,4-trimethyl-6-oxo-2,6-dihydroquinoline (4071-18-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Na₂CO₃; 2.) HBr / 1.) water, 3 deg C; 2.) H₂O, reflux, 5 h

2: Ag₂O / acetone / 2 h

With hydrogen bromide; sodium carbonate; silver(l) oxide; In acetone;

DOI:10.1007/BF00773268

upstream raw materials:

2,2,4-trimethyl-6-hydroxy-1,2-dihydroquinoline

N,N'-diphenyl-1,4-phenylenediamine

2,2,4-trimethyl-6-ethoxy-1,2-dihydroquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 4071-18-5 2,2,4-trimethylquinolin-6-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send