2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide

Base Information

Chemical Name:2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide
CAS No.:6088-02-4
Molecular Formula:C20H24N2O3
Molecular Weight:340.4162
Hs Code.:
DSSTox Substance ID:DTXSID20976354

Synonyms:6088-02-4;CBMicro_007955;Oprea1_145853;DTXSID20976354;SMSF0013728;STK223153;AKOS003263415;CB10475;BIM-0007918.P001;SR-01000227203;SR-01000227203-1;2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide;2-{[1-Hydroxy-2-(4-methoxyphenyl)ethylidene]amino}-N-(2-methylpropyl)benzene-1-carboximidic acid

Suppliers and Price of 2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide

Chemical Property:

Vapor Pressure:1.28E-13mmHg at 25°C
Boiling Point:583.9°Cat760mmHg
Flash Point:306.9°C
Density:1.144g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:340.17869263
Heavy Atom Count:25
Complexity:431

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CNC(=O)C1=CC=CC=C1NC(=O)CC2=CC=C(C=C2)OC

Technology Process of 2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide

There total 5 articles about 2-{[(4-methoxyphenyl)acetyl]amino}-N-(2-methylpropyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: (Z)-(4-²H)-tert-butyl((3-methylbut-3-en-1-yl)oxy)diphenylsilane

: 6088-02-4
(Z)-<4-2H>-3-methyl-3-buten-1-ol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
DOI:10.1002/anie.201800385

Reference yield:

: 74723-01-6
(Z)-4-bromo-3-methyl-3-buten-1-ol

: 6088-02-4
(Z)-<4-2H>-3-methyl-3-buten-1-ol

Guidance literature:: With trifluoroacetic acid-d₁; sec.-butyllithium; Multistep reaction; 1.) Et₂O, -90 deg C, 1.5 h;

Reference yield:

: 10518-50-0
3,4-dibromo-3-methyl-butan-1-ol

: 6088-02-4
(Z)-<4-2H>-3-methyl-3-buten-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 25 percent / 5M methanolic KOH / 2 h / 25 °C

2: 78 percent / imidazole / dimethylformamide / 0.08 h

3: 1.) tert-butyllithium, N,N,N',N'-tetramethylethylenediamine, 2.) trifluoroacetic acid 1-d / 1.) THF, ether, pentane, -78 deg C, 5 min, 2.) THF, ether, pentane, from -75 deg C to 0 deg C, 5 min

4: tetra(n-butyl)ammonium fluoride / tetrahydrofuran / 0.17 h

With 1H-imidazole; potassium hydroxide; N,N,N,N,-tetramethylethylenediamine; tetrabutyl ammonium fluoride; tert.-butyl lithium; trifluoroacetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1139/v94-019