4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one

Base Information

Chemical Name:4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one
CAS No.:87696-89-7
Molecular Formula:C16H16ClNOS
Molecular Weight:305.828
Hs Code.:
DSSTox Substance ID:DTXSID90520303
Wikidata:Q82384106

Synonyms:87696-89-7;DTXSID90520303;4-[(2-AMINO-4-CHLOROPHENYL)SULFANYL]-1-PHENYLBUTAN-1-ONE

Suppliers and Price of 4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:305.0641130
Heavy Atom Count:20
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CCCSC2=C(C=C(C=C2)Cl)N

Technology Process of 4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one

There total 1 articles about 4-[(2-Amino-4-chlorophenyl)sulfanyl]-1-phenylbutan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 615-48-5
2-amino-4-chloro-benzenethiol hydrochloride

: 939-52-6
4-chloro-1-phenylbutan-1-one

: 87696-89-7
4-(2-Amino-4-chlorophenylthio)butyrophenone

Guidance literature:: With sodium methylate; Yield given. Multistep reaction; 1.) methanol, 0.5 h, 2.) 3h, reflux;
DOI:10.1021/jo00175a024

Reference yield: 54.0%

: 87696-89-7
4-(2-Amino-4-chlorophenylthio)butyrophenone

: 76293-52-2
8-chloro-3,4-dihydro-5-phenyl-2H-1,6-benzothiazocine

Guidance literature:: toluene-4-sulfonic acid; In toluene; for 18h; Heating;
DOI:10.1021/jo00175a024

Reference yield:

: 87696-89-7
4-(2-Amino-4-chlorophenylthio)butyrophenone

: 87697-24-3
6-chloro-3-phenyl-2H-1,4-benzothiazine-Δ^2,α-acetaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / p-toluenesulfonic acid / toluene / 18 h / Heating

2: lead tetraacetate / acetic acid / 75 °C / overnight

With lead(IV) acetate; toluene-4-sulfonic acid; In acetic acid; toluene;
DOI:10.1021/jo00175a024