10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole

Base Information

Chemical Name:10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole
CAS No.:87699-03-4
Molecular Formula:C19H19N
Molecular Weight:261.367
Hs Code.:
DSSTox Substance ID:DTXSID10530540
Wikidata:Q82401747

Synonyms:10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole;87699-03-4;DTXSID10530540

Suppliers and Price of 10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:261.151749610
Heavy Atom Count:20
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN2C(=C(C3=CC=CC=C32)CC4=CC=CC=C4)C1

Technology Process of 10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole

There total 4 articles about 10-Benzyl-6,7,8,9-tetrahydropyrido[1,2-a]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

: 87698-89-3,87698-90-6
α-(Phenylmethylene)-2-(1-piperidinyl)-benzeneacetonitrile

: 87699-03-4
6,7,8,9-Tetrahydro-10-(phenylmethyl)pyrido<1,2-a>indole

: 87699-01-2
6,7,8,9,9a,10-Hexahydro-10-(phenylmethyl)pyrido<1,2-a>indole-10-carbonitrile

Guidance literature:: With zinc(II) chloride; In toluene; at 110 ℃; for 192h;
DOI:10.1021/jo00176a011

Reference yield:

: 111-24-0
1,5-dibromo-pentane

: 87699-03-4
6,7,8,9-Tetrahydro-10-(phenylmethyl)pyrido<1,2-a>indole

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / ethyldiisopropylamine / toluene / 18 h / 110 °C

2: 92 percent / NaOC₂H₅ / ethanol / 3 h / 78.5 °C

3: 26 percent / ZnCl₂ / toluene / 192 h / 110 °C

With sodium ethanolate; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; In ethanol; toluene;
DOI:10.1021/jo00176a011

Reference yield:

: 2973-50-4
2-aminophenylacetonitrile

: 87699-03-4
6,7,8,9-Tetrahydro-10-(phenylmethyl)pyrido<1,2-a>indole

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / ethyldiisopropylamine / toluene / 18 h / 110 °C

2: 92 percent / NaOC₂H₅ / ethanol / 3 h / 78.5 °C

3: 26 percent / ZnCl₂ / toluene / 192 h / 110 °C

With sodium ethanolate; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; In ethanol; toluene;
DOI:10.1021/jo00176a011