Anthranilic acid, N-(p-trifluoromethoxyphenyl)-

Base Information

Chemical Name:Anthranilic acid, N-(p-trifluoromethoxyphenyl)-
CAS No.:51679-41-5
Molecular Formula:C14H10 F3 N O3
Molecular Weight:297.234
Hs Code.:2922509090
DSSTox Substance ID:DTXSID40199624
Nikkaji Number:J2.060.401H
Mol file:51679-41-5.mol

Synonyms:51679-41-5;Anthranilic acid, N-(p-trifluoromethoxyphenyl)-;N-(p-Trifluoromethoxyphenyl)anthranilic acid;BRN 2758879;Benzoic acid, 2-((4-(trifluoromethoxy)phenyl)amino)-;2-[4-(trifluoromethoxy)anilino]benzoic acid;1,6-Naphthalenedisulfonicacid;N-(4-TRIFLUOROMETHOXYPHENYL)ANTHRANILIC ACID;Benzoic acid,2-[[4-(trifluoromethoxy)phenyl]amino]-;DTXSID40199624;YZBGUDOBFPDWKS-UHFFFAOYSA-N;AKOS012847667;LS-20578;2-(4-(trifluoromethoxy)phenylamino)benzoic acid

Suppliers and Price of Anthranilic acid, N-(p-trifluoromethoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4-TRIFLUOROMETHOXYPHENYL)ANTHRANILIC ACID 95.00%
5MG
$ 502.36

Total 3 raw suppliers

Chemical Property of Anthranilic acid, N-(p-trifluoromethoxyphenyl)-

Chemical Property:

Vapor Pressure:2.03E-06mmHg at 25°C
Boiling Point:379 °C at 760 mmHg
Flash Point:183 °C
PSA：58.56000
Density:1.426 g/cm³
LogP:4.10000
XLogP3:5.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:297.06127767
Heavy Atom Count:21
Complexity:354

Purity/Quality:

99% ^*data from raw suppliers

N-(4-TRIFLUOROMETHOXYPHENYL)ANTHRANILIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)O)NC2=CC=C(C=C2)OC(F)(F)F

Technology Process of Anthranilic acid, N-(p-trifluoromethoxyphenyl)-

There total 5 articles about Anthranilic acid, N-(p-trifluoromethoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 741280-97-7
methyl 2-[4-(trifluoromethoxy)anilino]benzoate

: 51679-41-5
2-(4-trifluoromethoxyphenylamino)benzoic acid

Guidance literature:: With sodium hydroxide; In water; acetone; at 20 ℃;
DOI:10.1016/j.tet.2004.05.013

Reference yield: 56.0%

: 88-67-5
2-Iodobenzoic acid

: 461-82-5
4-(trifluoromethoxy)aniline

: 51679-41-5
2-(4-trifluoromethoxyphenylamino)benzoic acid

Guidance literature:: With copper(l) iodide; copper; potassium carbonate; In N,N-dimethyl-formamide; for 2h; Inert atmosphere;
DOI:10.1016/j.ejmech.2020.112193

Reference yield:

: 461-82-5
4-(trifluoromethoxy)aniline

: 51679-41-5
2-(4-trifluoromethoxyphenylamino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / DPE-Phos; Cs₂CO₃ / Pd(OAc)2 / toluene / 48 h / 95 °C

2: 95 percent / NaOH / acetone; H₂O / 20 °C

With sodium hydroxide; DPE-Phos; caesium carbonate; palladium diacetate; In water; acetone; toluene; 1: Buchwald-Hartwig amination reaction;
DOI:10.1016/j.tet.2004.05.013