5-(Iodomethyl)-4-phenyloxolan-2-one

Base Information

Chemical Name:5-(Iodomethyl)-4-phenyloxolan-2-one
CAS No.:87761-90-8
Molecular Formula:C11H11IO2
Molecular Weight:302.10800
Hs Code.:
DSSTox Substance ID:DTXSID10520209
Nikkaji Number:J363.501E

Synonyms:5-(Iodomethyl)-4-phenyloxolan-2-one;87761-90-8;SCHEMBL9655969;DTXSID10520209

Suppliers and Price of 5-(Iodomethyl)-4-phenyloxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(Iodomethyl)-4-phenyloxolan-2-one

Chemical Property:

PSA：26.30000
LogP:2.52070
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:301.98038
Heavy Atom Count:14
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1=O)CI)C2=CC=CC=C2

Technology Process of 5-(Iodomethyl)-4-phenyloxolan-2-one

There total 10 articles about 5-(Iodomethyl)-4-phenyloxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 5703-57-1,132032-89-4
3-phenylpent-4-enoic acid

: 67279-69-0,67279-70-3,87761-90-8,131323-48-3,131352-00-6
trans-4,5-dihydro-5-iodomethyl-4-phenyl-2(3H)-furanone

Guidance literature:: With iodine; In acetonitrile; at 0 ℃; for 24h; Inert atmosphere; Darkness;
DOI:10.1039/c3ob27321k

Reference yield:

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 67279-69-0,67279-70-3,87761-90-8,131323-48-3,131352-00-6
trans-4,5-dihydro-5-iodomethyl-4-phenyl-2(3H)-furanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1) Propionsaeure, 2a) conc. HCl, 2b) H₂O/methanol/KOH / 1) 140-150 deg C, 2a) 110 deg C, 2b) reflux, 2h

2: NaHCO₃, KI, I₂ / acetonitrile / 12 h / Ambient temperature

With hydrogenchloride; methanol; potassium hydroxide; water; iodine; sodium hydrogencarbonate; propionic acid; potassium iodide; In acetonitrile;

Reference yield:

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 67279-69-0,67279-70-3,87761-90-8,131323-48-3,131352-00-6
cis-4,5-dihydro-5-iodomethyl-4-phenyl-2(3H)-furanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1) Propionsaeure, 2a) conc. HCl, 2b) H₂O/methanol/KOH / 1) 140-150 deg C, 2a) 110 deg C, 2b) reflux, 2h

2: NaHCO₃, KI, I₂ / acetonitrile / 12 h / Ambient temperature

With hydrogenchloride; methanol; potassium hydroxide; water; iodine; sodium hydrogencarbonate; propionic acid; potassium iodide; In acetonitrile;