N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide

Base Information

Chemical Name:N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide
CAS No.:87762-08-1
Molecular Formula:C16H13Cl2NO4
Molecular Weight:354.19
Hs Code.:
DSSTox Substance ID:DTXSID00528370
Wikidata:Q82397947

Synonyms:87762-08-1;DTXSID00528370;N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide

Suppliers and Price of N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:353.0221633
Heavy Atom Count:23
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C2=C(C(=C(C=C2)NC(=O)CO)Cl)Cl

Technology Process of N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide

There total 2 articles about N-[2,3-Dichloro-4-(4-methoxybenzoyl)phenyl]-2-hydroxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 87762-04-7
2-[2,3-Dichloro-4-(4-methoxy-benzoyl)-phenoxy]-acetamide

: 87762-08-1
N-[2,3-Dichloro-4-(4-methoxy-benzoyl)-phenyl]-2-hydroxy-acetamide

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 1.25h; Ambient temperature;
DOI:10.1021/jo00173a076

Reference yield:

: 87762-02-5
[2,3-Dichloro-4-(4-methoxy-benzoyl)-phenoxy]-acetic acid ethyl ester

: 87762-08-1
N-[2,3-Dichloro-4-(4-methoxy-benzoyl)-phenyl]-2-hydroxy-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃ / ethanol

2: 48 percent / NaH / dimethylformamide / 1.25 h / Ambient temperature

With ammonia; sodium hydride; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00173a076