5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy-

Base Information

Chemical Name:5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy-
CAS No.:87782-03-4
Molecular Formula:C₂₀H₂₆N₅O₇P
Molecular Weight:479.429
Hs Code.:

Synonyms:

Suppliers and Price of 5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy-

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy-

There total 10 articles about 5'-Guanylic acid, N-(4-butylphenyl)-2'-deoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (4-Butyl-phenyl)-trimethylsilanyl-(9-trimethylsilanyl-6-trimethylsilanyloxy-9H-purin-2-yl)-amine

: 87782-03-4
N²-(p-n-butylphenyl)-2'-deoxyguanosine 5'-phosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) trimethylsilyl trifluoromethanesulfonate, 2.) NaOCH₃ / 1.) 1,2-dichloroethane, benzene, RT, 2 h, 2.) 60 deg C, 1 h

2: 1.) POCl₃, trimethyl phosphate, 2.) Et₃N / 1.) 0 deg C - 5 deg C

With trimethyl phosphite; trimethylsilyl trifluoromethanesulfonate; sodium methylate; triethylamine; trichlorophosphate;
DOI:10.1021/jm00368a012

Reference yield:

: 41623-91-0
2-bromo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)hypoxanthine

: 87782-03-4
N²-(p-n-butylphenyl)-2'-deoxyguanosine 5'-phosphate

Guidance literature:: Multi-step reaction with 7 steps

1: 56 percent / 2-methoxy-ethanol / 1.5 h / Heating

2: 98 percent / aq. NH₃ / ethanol / 72 h

3: 81 percent / pyridine / Ambient temperature

4: 83 percent / dimethylformamide / 4.5 h / 35 °C

5: 92 percent / tri-n-butyltin hydride, 2,2'-azobis<2-methylpropionitrile> / toluene / 2 h / Heating

6: 87.4 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h

7: 1.) POCl₃, trimethyl phosphate, 2.) Et₃N / 1.) 0 deg C - 5 deg C

With pyridine; trimethyl phosphite; ammonium hydroxide; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; triethylamine; trichlorophosphate; In tetrahydrofuran; ethanol; 2-methoxy-ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00368a012

Reference yield:

: 2-Bromo-9-trimethylsilanyl-6-trimethylsilanyloxy-9H-purine

: 87782-03-4
N²-(p-n-butylphenyl)-2'-deoxyguanosine 5'-phosphate

Guidance literature:: Multi-step reaction with 8 steps

1: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 0.25 h / Heating

2: 56 percent / 2-methoxy-ethanol / 1.5 h / Heating

3: 98 percent / aq. NH₃ / ethanol / 72 h

4: 81 percent / pyridine / Ambient temperature

5: 83 percent / dimethylformamide / 4.5 h / 35 °C

6: 92 percent / tri-n-butyltin hydride, 2,2'-azobis<2-methylpropionitrile> / toluene / 2 h / Heating

7: 87.4 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h

8: 1.) POCl₃, trimethyl phosphate, 2.) Et₃N / 1.) 0 deg C - 5 deg C

With pyridine; trimethyl phosphite; ammonium hydroxide; 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; triethylamine; trichlorophosphate; In tetrahydrofuran; ethanol; 2-methoxy-ethanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1021/jm00368a012