tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester

Base Information

• Chemical Name: tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester
• CAS No.: 114396-65-5
• Molecular Formula: C₁₅H₂₈N₂O₆
• Molecular Weight: 332.397
• Mol file: 114396-65-5.mol

Synonyms:tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester

Chemical Property of tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester

Chemical Property:

• Vapor Pressure: 1.01E-12mmHg at 25°C
• Boiling Point: 514.2°Cat760mmHg
• Flash Point: 264.8°C
• PSA: 113.96000
• Density: 1.122g/cm³
• LogP: 1.35770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester

There total 1 articles about tert-butyloxycarbonyl-valyl-alpha-methylserine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

t-Boc-L-valine (13734-41-3) + (S)-methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride (114396-63-3,134899-86-8) → Boc-Val-α-MeSer-OMe (114396-65-5)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 15h; Ambient temperature;

upstream raw materials:

t-Boc-L-valine

(S)-methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride

Refernces