Azacycloundecane-2-carboxylic acid

Base Information

• Chemical Name: Azacycloundecane-2-carboxylic acid
• CAS No.: 14026-69-8
• Molecular Formula: C11H21NO2
• Molecular Weight: 199.2899
• Mol file: 14026-69-8.mol

Synonyms:

Chemical Property of Azacycloundecane-2-carboxylic acid

Chemical Property:

• Vapor Pressure: 1.11E-05mmHg at 25°C
• Boiling Point: 345.3°C at 760 mmHg
• Flash Point: 162.6°C
• Density: 0.979g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Azacycloundecane-2-carboxylic acid

There total 4 articles about Azacycloundecane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H29NO4 → (+/-)-Azacycloundecan-2-carbonsaeure (14026-69-8)

Guidance literature:

C₁₆H₂₉NO₄; With water; sodium hydroxide; at 20 ℃;

With acetic acid; at 90 ℃; for 4h; pH=5 - 6;

Reference yield:

diethyl 2-Boc-2-(10-chlorodecyl)aminomalonate → (+/-)-Azacycloundecan-2-carbonsaeure (14026-69-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride / ethyl acetate / 20 °C / Cooling; Inert atmosphere

2.1: sodium iodide; potassium carbonate / acetonitrile / 80 °C / Inert atmosphere

3.1: sodium hydroxide; water / 20 °C

3.2: 4 h / 90 °C / pH 5 - 6

With hydrogenchloride; water; potassium carbonate; sodium iodide; sodium hydroxide; In ethyl acetate; acetonitrile;

Reference yield:

2-amino-2-(10-chlorodecyl)-malonic acid diethyl ester → (+/-)-Azacycloundecan-2-carbonsaeure (14026-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium iodide; potassium carbonate / acetonitrile / 80 °C / Inert atmosphere

2.1: sodium hydroxide; water / 20 °C

2.2: 4 h / 90 °C / pH 5 - 6

With water; potassium carbonate; sodium iodide; sodium hydroxide; In acetonitrile;

Refernces