1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde

Base Information

Chemical Name:1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde
CAS No.:87948-07-0
Molecular Formula:C₁₂H₁₁N₃O₃
Molecular Weight:245.238
Hs Code.:
DSSTox Substance ID:DTXSID10522824
Wikidata:Q82388447

Synonyms:87948-07-0;1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde;DTXSID10522824

Suppliers and Price of 1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:245.08004122
Heavy Atom Count:18
Complexity:318

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=CC=CC=C1[N+](=O)[O-])N2C=CC=C2C=O

Technology Process of 1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde

There total 3 articles about 1-[Methyl(2-nitrophenyl)amino]-1H-pyrrole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 87948-03-6
N-Methyl-N-(2-nitrophenyl)-1H-pyrrol-1-amine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 87948-07-0
N-Methyl-N-(2-nitrophenyl)-2-formyl-1H-pyrrol-1-amine

Guidance literature:: With trichlorophosphate; 1.) 0-5 deg C, 15 min, 2.) 110-120 deg C, 2.5 h;
DOI:10.1055/s-1983-30503

Reference yield:

: 79700-48-4
N-(2-nitrophenyl)-1H-pyrrol-1-ylamine

: 87948-07-0
N-Methyl-N-(2-nitrophenyl)-2-formyl-1H-pyrrol-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / NaH / tetrahydrofuran / 18 h / 80 °C

2: 71 percent / 1.) POCl₃ / 1.) 0-5 deg C, 15 min, 2.) 110-120 deg C, 2.5 h

With sodium hydride; trichlorophosphate; In tetrahydrofuran;
DOI:10.1055/s-1983-30503

Reference yield:

: 3034-19-3
(2-nitrophenyl)hydrazine

: 87948-07-0
N-Methyl-N-(2-nitrophenyl)-2-formyl-1H-pyrrol-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / HCl(g) / ethanol / 0.5 h / Heating

2: 98 percent / NaH / tetrahydrofuran / 18 h / 80 °C

3: 71 percent / 1.) POCl₃ / 1.) 0-5 deg C, 15 min, 2.) 110-120 deg C, 2.5 h

With hydrogenchloride; sodium hydride; trichlorophosphate; In tetrahydrofuran; ethanol;
DOI:10.1055/s-1983-30503