Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride

Base Information

Chemical Name:Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride
CAS No.:99633-74-6
Molecular Formula:C₂₂H₂₉N₃O*2ClH
Molecular Weight:424.414
Hs Code.:
DSSTox Substance ID:DTXSID90912582

Synonyms:99633-74-6;Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride;DTXSID90912582;LS-9104;2-(Diethylamino)-N-(2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-yl)ethanimidic acid--hydrogen chloride (1/2)

Suppliers and Price of Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride

Chemical Property:

Vapor Pressure:3.06E-10mmHg at 25°C
Boiling Point:502.9°Cat760mmHg
Flash Point:257.9°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:423.1844180
Heavy Atom Count:28
Complexity:445

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)CC(=O)NC1=CC=CC2=C1CN(CC2C3=CC=CC=C3)C.Cl.Cl

Technology Process of Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride

There total 3 articles about Acetamide, 2-(diethylamino)-N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolyl)-, dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 99633-80-4
2-Diethylamino-N-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-yl)-acetamide

: 99633-74-6
2-Diethylamino-N-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-yl)-acetamide; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; Yield given;

Reference yield:

: 24526-64-5
nomifensine

: 99633-74-6
2-Diethylamino-N-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-yl)-acetamide; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / K₂CO₃ / acetone / 0.5 h / Heating

2: benzene / Heating

3: ethanolic HCl / ethanol

With hydrogenchloride; potassium carbonate; In ethanol; acetone; benzene;

Reference yield:

: 99633-72-4
4-phenyl-8-<(chloroacetyl)amino>-2-methyl-1,2,3,4-tetrahydroisoquinoline

: 99633-74-6
2-Diethylamino-N-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-yl)-acetamide; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / Heating

2: ethanolic HCl / ethanol

With hydrogenchloride; In ethanol; benzene;