4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Base Information

Chemical Name:4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS No.:88059-53-4
Molecular Formula:C₁₄H₁₁N₃O
Molecular Weight:237.261
Hs Code.:
DSSTox Substance ID:DTXSID80354114
Nikkaji Number:J1.976.012J
Wikidata:Q82132079
ChEMBL ID:CHEMBL1546177

Synonyms:4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine;88059-53-4;5-(4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole;MLS001165213;SMR000549728;BAS 01416151;Oprea1_443486;Oprea1_666730;cid_763855;CHEMBL1546177;BDBM93884;DTXSID80354114;HMS2857J24;STK205811;AKOS000618652;8K-562S;5-(p-tolyl)-3-(4-pyridyl)-1,2,4-oxadiazole;SR-01000501759;SR-01000501759-1

Suppliers and Price of 4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine

Chemical Property:

Melting Point:136-137 °C(Solv: acetone (67-64-1); water (7732-18-5))
Boiling Point:420.6±55.0 °C(Predicted)
PSA：51.81000
Density:1.193±0.06 g/cm3(Predicted)
LogP:3.10700
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:237.090211983
Heavy Atom Count:18
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC(=NO2)C3=CC=NC=C3

Technology Process of 4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine

There total 2 articles about 4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 63824-98-6
4-Methyl-N-pyridin-4-ylmethyl-benzamide

: 88059-53-4
5-(4-methylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole

Guidance literature:: With nitrosylchloride; In chloroform; Ambient temperature; overnight;
DOI:10.1002/jhet.5570200548

Reference yield:

: 1594-57-6,849833-58-5
isonicotinamidoxime

: 99-94-5
p-Toluic acid

: 88059-53-4
5-(4-methylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 191 ℃; for 0.0333333h; microwave irradiation;
DOI:10.1016/j.tetlet.2003.10.055