Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate

Base Information

Chemical Name:Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate
CAS No.:88061-85-2
Molecular Formula:C9H7N3O4
Molecular Weight:221.17000
Hs Code.:
DSSTox Substance ID:DTXSID00516156
Wikidata:Q82377443
Mol file:88061-85-2.mol

Synonyms:88061-85-2;Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate;3-Nitro-imidazo[1,2-a]pyridine-5-carboxylic acid methyl ester;DTXSID00516156;G10954;3-Nitroimidazo[1,2-a]pyridine-5-carboxylic acid methyl ester

Suppliers and Price of Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Nitro-imidazo[1,2-a]pyridine-5-carboxylicAcidmethylester
100mg
$ 155.00

Chemcia Scientific
3-Nitro-imidazo[1,2-a]pyridine-5-carboxylicacidmethylester ＞95%
1 G
$ 350.00

Total 3 raw suppliers

Chemical Property of Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate

Chemical Property:

PSA：89.42000
LogP:1.55230
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:221.04365571
Heavy Atom Count:16
Complexity:304

Purity/Quality:: 3-Nitro-imidazo[1,2-a]pyridine-5-carboxylicAcidmethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=CC2=NC=C(N21)[N+](=O)[O-]

Technology Process of Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate

There total 3 articles about Methyl 3-nitroimidazo[1,2-a]pyridine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 88047-55-6
methyl imidazo<1,2-a>pyridine-5-carboxylate

: 88061-85-2
methyl 3-nitroimidazo<1,2-a>pyridine-5-carboxylate

Guidance literature:: With sulfuric acid; nitric acid;

Reference yield:

: 36052-26-3
methyl 6-aminopyridine-2-carboxylate

: 88061-85-2
methyl 3-nitroimidazo<1,2-a>pyridine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 50percent HCl, 2.) NaHCO₃ / 1.) H₂O, reflux, 3 h, 2.) ethanol, reflux, 16 h

2: 80 percent / fuming nitric acid, conc. sulphuric acid

With hydrogenchloride; sulfuric acid; nitric acid; sodium hydrogencarbonate;