[1-(Benzenesulfonyl)cyclopentyl]sulfonylbenzene

Base Information

• Chemical Name: [1-(Benzenesulfonyl)cyclopentyl]sulfonylbenzene
• CAS No.: 88073-51-2
• Molecular Formula: C17H18O4S2
• Molecular Weight: 350.46
• DSSTox Substance ID: DTXSID70362485
• Nikkaji Number: J2.527.055J
• Wikidata: Q82145607
• Pharos Ligand ID: RW91V6W5JUCJ
• ChEMBL ID: CHEMBL1576177
• Mol file: 88073-51-2.mol

Synonyms:MLS000105099;SMR000055028;[1-(benzenesulfonyl)cyclopentyl]sulfonylbenzene;HMS2370I07;88073-51-2;Enamine_000050;Benzene, 1,1'-[cyclopentylidenebis(sulfonyl)]bis-;SCHEMBL3193854;CHEMBL1576177;BDBM46856;cid_1380165;DTXSID70362485;HMS1394C06;(1-besylcyclopentyl)sulfonylbenzene;1,1-bis(phenylsulfonyl)cyclopentane;AKOS001030517;[1-(phenylsulfonyl)cyclopentyl]sulfonylbenzene;1,1'-(1,1-cyclopentanediyldisulfonyl)dibenzene;SR-01000196853;SR-01000196853-1;Z56759801

Chemical Property of [1-(Benzenesulfonyl)cyclopentyl]sulfonylbenzene

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 350.06465140
• Heavy Atom Count: 23
• Complexity: 542

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)(S(=O)(=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=CC=C3

Technology Process of [1-(Benzenesulfonyl)cyclopentyl]sulfonylbenzene

There total 17 articles about [1-(Benzenesulfonyl)cyclopentyl]sulfonylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,4-dibromo-butane (110-52-1) + bis(phenylsulfonyl)methane (3406-02-8) → 1,1-bis(benzenesulphonyl)cyclopentane (88073-51-2)

Guidance literature:

tetrabutylammomium bromide; In sodium hydroxide; at 25 - 30 ℃; for 3h;

Reference yield: 97.0%

5-chloro-1,1-bis(phenylsulphonyl)pentane (89593-87-3) → 1,1-bis(benzenesulphonyl)cyclopentane (88073-51-2)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 6h;

Reference yield: 95.0%

5,5-bis(benzenesulphonyl)pentyl ethyl 4-methylphenyl sulphonium tetrafluoroborate → ethyl p-tolyl sulfide (622-63-9) + 1,1-bis(benzenesulphonyl)cyclopentane (88073-51-2)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 4h;

upstream raw materials:

1,4-dibromo-butane

bis(phenylsulfonyl)methane

5-chloro-1,1-bis(phenylsulphonyl)pentane

1,1-bis(benzenesulphonyl)-5-iodopentane

Downstream raw materials:

(cyclopentylsulfonyl)benzene

Refernces

• 1、 Benedetti, Fabio,Fabrissin, Silvio,Rusconi, Alessandro,Stirling, Charles J. M.. "TRANSITION STATES IN INTRAMOLECULAR SN2 REACTIONS OF CARBANIONS. THE CLOSURE OF THREE-, FOUR- AND FIVE-MEMBERED RINGS". . p. 233 - 240. Retrieved 2007/10/02.
• 2、 Benedetti, Fabio,Stirling, Charles J.M.. "Elimination and Addition Reactions. Part 40. The Insignificant Effect of Strain in Higher Order Eliminations in 1,1-bis(phenylsulphonyl) Carbanions with ω-Leaving Groups". . p. 605 - 612. Retrieved 2007/10/02.