(2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate

Base Information

Chemical Name:(2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate
CAS No.:88081-65-6
Molecular Formula:C10H11ClO4S
Molecular Weight:262.714
Hs Code.:
DSSTox Substance ID:DTXSID00509240
Nikkaji Number:J74.329A

Synonyms:88081-65-6;SCHEMBL5099695;DTXSID00509240;XFKAMBULGKHYIY-MRVPVSSYSA-N;(2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate;(1R)-2-chloro-1-methyl-2-oxoethyl p-toluenesulphonate

Suppliers and Price of (2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:262.0066577
Heavy Atom Count:16
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OC(C)C(=O)Cl
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)O[C@H](C)C(=O)Cl

Technology Process of (2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate

There total 4 articles about (2R)-1-Chloro-1-oxopropan-2-yl 4-methylbenzene-1-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 130368-69-3
(2R)-2-(4-Toluenesulfonyloxy)propionic Acid

: 88081-65-6
(2R)-2-(4-toluenesulfonyloxy)propionyl chloride

Guidance literature:: With thionyl chloride; Edukt 1 ist ein partiell racemisches Praeparat;
DOI:10.1039/jr9360000303

Reference yield:

: 88081-65-6
(2R)-2-(4-toluenesulfonyloxy)propionyl chloride

Guidance literature:: With thionyl chloride; at 60 - 70 ℃;

Reference yield:

: 109579-04-6
methyl (2R)-2-{[(4-methylphenyl)sulfonyl]oxy}propanoate

: 88081-65-6
(2R)-2-(4-toluenesulfonyloxy)propionyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / 10percent NaOH / H₂O / a) 5-10 deg C, 15 min, b) r.t., 45 min

2: SOCl₂ / CHCl₃ / 3 h / Heating

With sodium hydroxide; thionyl chloride; In chloroform; water;
DOI:10.1248/cpb.39.1374