3-(2,4-Dimethylphenyl)-2H-azirene

Base Information

• Chemical Name: 3-(2,4-Dimethylphenyl)-2H-azirene
• CAS No.: 88089-31-0
• Molecular Formula: C10H11N
• Molecular Weight: 145.204
• DSSTox Substance ID: DTXSID70526065
• Wikidata: Q82394203

Synonyms:3-(2,4-dimethylphenyl)-2H-azirine;88089-31-0;3-(2,4-Dimethylphenyl)-2H-azirene;DTXSID70526065

Chemical Property of 3-(2,4-Dimethylphenyl)-2H-azirene

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 145.089149355
• Heavy Atom Count: 11
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C2=NC2)C

Technology Process of 3-(2,4-Dimethylphenyl)-2H-azirene

There total 2 articles about 3-(2,4-Dimethylphenyl)-2H-azirene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dimethylstyrene (2234-20-0) → 2-(2,4-dimethylphenyl)azirine (88089-31-0)

Guidance literature:

Multi-step reaction with 4 steps

1: bromine / tetrachloromethane / 2 h / 20 °C

2: sodium azide / dimethyl sulfoxide / 13 h / 20 °C / Inert atmosphere

3: sodium hydroxide / 24 h / 20 °C

4: toluene / 4 h / Reflux

With sodium azide; bromine; sodium hydroxide; In tetrachloromethane; dimethyl sulfoxide; toluene;

DOI:10.1021/acs.joc.9b01625

Reference yield:

C10H11N3 → 2-(2,4-dimethylphenyl)azirine (88089-31-0)

Guidance literature:

In toluene; for 4h; Reflux;

DOI:10.1021/acs.joc.9b01625

Reference yield: 88.0%

2-(2,4-dimethylphenyl)azirine (88089-31-0) + trifluoroacetic acid (76-05-1) → N-(2-(2,4-dimethylphenyl)-2-oxoethyl)-2,2,2-trifluoroacetamide

Guidance literature:

In toluene; at 20 ℃; for 0.166667h; regioselective reaction;

DOI:10.1021/acs.orglett.0c01206

upstream raw materials:

2,4-dimethylstyrene

Downstream raw materials:

2-Benzenesulfonyl-3-(2,4-dimethyl-phenyl)-1-aza-bicyclo[1.1.0]butane

2,4-dimethylacetophenone.

N-(2-(2,4-dimethylphenyl)-2-oxoethyl)formamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 88089-31-0 2H-Azirine, 3-(2,4-dimethylphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send