(2-Amino-4-phenylbutyl)methylphosphinic acid

Base Information

Chemical Name:(2-Amino-4-phenylbutyl)methylphosphinic acid
CAS No.:88129-53-7
Molecular Formula:C₁₁H₁₈NO₂P
Molecular Weight:227.243
Hs Code.:
DSSTox Substance ID:DTXSID40521840

Synonyms:88129-53-7;(2-Amino-4-phenylbutyl)methylphosphinic acid;DTXSID40521840

Suppliers and Price of (2-Amino-4-phenylbutyl)methylphosphinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-Amino-4-phenylbutyl)methylphosphinic acid

Chemical Property:

XLogP3:-2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:227.10751581
Heavy Atom Count:15
Complexity:227

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CP(=O)(CC(CCC1=CC=CC=C1)N)O

Technology Process of (2-Amino-4-phenylbutyl)methylphosphinic acid

There total 2 articles about (2-Amino-4-phenylbutyl)methylphosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 761373-40-4
(βR)-β-amino-benzenebutanol

: 88129-53-7
((R)-2-Amino-4-phenyl-butyl)-methyl-phosphinic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / pyridine / 0 °C

2: 95 percent / tetrahydrofuran / 3 h / Ambient temperature

3: 66 percent / 48percent HBr-phenol / 3 h / Heating

With hydrogen bromide; phenol; In tetrahydrofuran; pyridine;
DOI:10.1016/S0040-4039(00)88062-4

Reference yield:

: 87601-39-6
Toluene-4-sulfonic acid (R)-4-phenyl-2-(toluene-4-sulfonylamino)-butyl ester

: 88129-53-7
((R)-2-Amino-4-phenyl-butyl)-methyl-phosphinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / tetrahydrofuran / 3 h / Ambient temperature

2: 66 percent / 48percent HBr-phenol / 3 h / Heating

With hydrogen bromide; phenol; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)88062-4