2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine

Base Information

Chemical Name:2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine
CAS No.:126318-00-1
Molecular Formula:C16H26NO+
Molecular Weight:248.3832
Hs Code.:2932999099
DSSTox Substance ID:DTXSID50389756
Mol file:126318-00-1.mol

Synonyms:126318-00-1;2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine;2-(4-benzyl-2,2-dimethyloxan-4-yl)ethanamine;2-(4-Benzyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine;TimTec1_008125;Oprea1_387987;Oprea1_547100;DTXSID50389756;HMS1557B07;STL560673;AKOS000588952;AKOS021610576;CCG-122723;CS-0334619;2-(4-Benzyl-2,2-dimethyloxan-4-yl)ethan-1-amine;2-(4-benzyl-2,2-dimethyl-tetrahydropyran-4-yl)ethylamine;[2-(4-benzyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethyl]amine;2-(4-Benzyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethan-1-amine

Suppliers and Price of 2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-BENZYL-2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-YL)-ETHYLAMINE 95.00%
5MG
$ 502.70

Total 2 raw suppliers

Chemical Property of 2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine

Chemical Property:

Vapor Pressure:5.82E-05mmHg at 25°C
Boiling Point:346.3°Cat760mmHg
Flash Point:149.8°C
PSA：35.25000
Density:g/cm³
LogP:3.85360
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:247.193614421
Heavy Atom Count:18
Complexity:258

Purity/Quality:

99% ^*data from raw suppliers

2-(4-BENZYL-2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-YL)-ETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(CCO1)(CCN)CC2=CC=CC=C2)C

Technology Process of 2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine

There total 4 articles about 2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 109878-47-9
(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-acetonitrile

: 126318-00-1
2,2-dimethyl-4-benzyl-4-β-aminoethyltetrahydropyran

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at -2 - 2 ℃; for 1h;
DOI:10.1007/BF00766251

Reference yield:

: 130688-12-9
2,2-dimethyl-4-benzyltetrahydropyran-4-ylacetamide

: 126318-00-1
2,2-dimethyl-4-benzyl-4-β-aminoethyltetrahydropyran

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; ethanol; for 20h; Ambient temperature;
DOI:10.1007/BF00766251

Reference yield:

: 109878-51-5
(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-acetic acid

: 126318-00-1
2,2-dimethyl-4-benzyl-4-β-aminoethyltetrahydropyran

Guidance literature:: Multi-step reaction with 3 steps

1: formamide, SOCl₂ / benzene / 1 h / 60 °C

2: 25percent aq. ammonia / 48 h / Ambient temperature

3: LiAlH₄ / ethanol; tetrahydrofuran / 20 h / Ambient temperature

With ammonium hydroxide; lithium aluminium tetrahydride; thionyl chloride; formamide; In tetrahydrofuran; ethanol; benzene;
DOI:10.1007/BF00766251