4-Bromo-2,3,5,6-tetramethylbenzaldehyde

Base Information

Chemical Name:4-Bromo-2,3,5,6-tetramethylbenzaldehyde
CAS No.:88174-44-1
Molecular Formula:C11H13BrO
Molecular Weight:241.128
Hs Code.:
European Community (EC) Number:890-970-9
DSSTox Substance ID:DTXSID10460550
Wikidata:Q82284623

Synonyms:4-bromo-2,3,5,6-tetramethylbenzaldehyde;88174-44-1;Benzaldehyde, 4-bromo-2,3,5,6-tetramethyl-;DTXSID10460550;BS-25806;EN300-22994049;Z3952166653

Suppliers and Price of 4-Bromo-2,3,5,6-tetramethylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-Bromo-2,3,5,6-tetramethylbenzaldehyde

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:240.01498
Heavy Atom Count:13
Complexity:177

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=C(C(=C1C=O)C)C)Br)C

Technology Process of 4-Bromo-2,3,5,6-tetramethylbenzaldehyde

There total 3 articles about 4-Bromo-2,3,5,6-tetramethylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1646-54-4
1,4-dibromodurene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 88174-44-1
4-bromo-2,3,5,6-tetramethylbenzaldehyde

Guidance literature:: 1,4-dibromodurene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Schlenk technique; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃; Schlenk technique; Inert atmosphere;
DOI:10.1021/jacs.5b04629

Reference yield: 86.0%

: 188984-14-7
4-bromo-2,3,5,6-tetramethylbenzonitrile

: 88174-44-1
4-bromo-2,3,5,6-tetramethylbenzaldehyde

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at 0 - 20 ℃; for 10h;
DOI:10.1021/jo048482a

Reference yield:

: 1646-54-4
1,4-dibromodurene

: 88174-44-1
4-bromo-2,3,5,6-tetramethylbenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 8 h / Heating

2: 86 percent / DIBALH / CH₂Cl₂ / 10 h / 0 - 20 °C

With diisobutylaluminium hydride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo048482a