(2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine

Base Information

Chemical Name:(2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine
CAS No.:88214-64-6
Molecular Formula:C₂₁H₁₉NO
Molecular Weight:301.388
Hs Code.:
DSSTox Substance ID:DTXSID00521361
Wikidata:Q82385786

Synonyms:88214-64-6;DTXSID00521361;(2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine

Suppliers and Price of (2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine

Chemical Property:

PSA：21.26000
LogP:5.43660
XLogP3:5.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:301.146664230
Heavy Atom Count:23
Complexity:359

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C2=CC=CC=C2OC1C3=CC=CC=C3)NC4=CC=CC=C4
Isomeric SMILES:C1[C@H](C2=CC=CC=C2O[C@H]1C3=CC=CC=C3)NC4=CC=CC=C4

Technology Process of (2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine

There total 6 articles about (2R,4R)-N,2-Diphenyl-3,4-dihydro-2H-1-benzopyran-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 88214-56-6,104819-59-2
trans-4-chloro-2-phenyl-3,4-dihydro-2H-chromene

: 62-53-3
aniline

: 88214-64-6,88214-67-9
Phenyl-((2R,4R)-2-phenyl-chroman-4-yl)-amine

: 88214-64-6,88214-67-9
Phenyl-((2S,4R)-2-phenyl-chroman-4-yl)-amine

Guidance literature:: In 1,4-dioxane; at 100 ℃;

Reference yield: 6.0%

: 88214-56-6,104819-59-2
trans-4-chloro-2-phenyl-3,4-dihydro-2H-chromene

: 62-53-3
aniline

: 88214-64-6,88214-67-9
Phenyl-((2R,4R)-2-phenyl-chroman-4-yl)-amine

: 88214-64-6,88214-67-9
Phenyl-((2S,4R)-2-phenyl-chroman-4-yl)-amine

Guidance literature:: In 1,4-dioxane; at 100 ℃;

Reference yield:

: 487-25-2,20107-47-5,20107-48-6,20902-95-8,26049-32-1,27439-08-3,41886-75-3,51196-78-2,51196-83-9
cis-4-hydroxyflavan

: 88214-64-6,88214-67-9
Phenyl-((2R,4R)-2-phenyl-chroman-4-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / diphenylphosphoryl chloride / pyridine / 0 °C

2: 16 percent / dioxane / 100 °C

With Diphenylphosphinic chloride; In 1,4-dioxane; pyridine;