2-Mercapto-3-(1-naphthalenyl)propenoic acid

Base Information

• Chemical Name: 2-Mercapto-3-(1-naphthalenyl)propenoic acid
• CAS No.: 88220-26-2
• Molecular Formula: C₁₃H₁₀O₂S
• Molecular Weight: 230.287
• Mol file: 88220-26-2.mol

Synonyms:

Chemical Property of 2-Mercapto-3-(1-naphthalenyl)propenoic acid

Chemical Property:

• PSA: 76.10000
• LogP: 3.19510

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Mercapto-3-(1-naphthalenyl)propenoic acid

There total 1 articles about 2-Mercapto-3-(1-naphthalenyl)propenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.3%

5-(1-naphthylidene)rhodanine (65562-51-8) → 3-(1'-naphthyl)-2-thiopropenoic acid (88220-26-2)

Guidance literature:

With sodium hydroxide; In water; at 60 ℃; for 0.833333h; Cooling;

Reference yield:

3-(1'-naphthyl)-2-thiopropenoic acid (88220-26-2) → 2-styrylnaphtho<2,1-b>thiophene (88220-28-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 82 percent / I₂ / dioxane / 20 h / 45 °C

2: 89 percent / LiAlH₄ / diethyl ether / Heating

3: 78 percent / CrO₃ / pyridine

4: 1.) NaH / 1.) DME

With chromium(VI) oxide; lithium aluminium tetrahydride; iodine; sodium hydride; In 1,4-dioxane; pyridine; diethyl ether;

Reference yield:

3-(1'-naphthyl)-2-thiopropenoic acid (88220-26-2) → 2-naphtho<2,1-b>thienylmethanol (30689-48-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / I₂ / dioxane / 20 h / 45 °C

2: 89 percent / LiAlH₄ / diethyl ether / Heating

With lithium aluminium tetrahydride; iodine; In 1,4-dioxane; diethyl ether;

upstream raw materials:

5-(1-naphthylidene)rhodanine

Downstream raw materials:

2-naphtho<2,1-b>thienylmethanol

2-styrylnaphtho<2,1-b>thiophene

Refernces