2-Acryloylbenzoic acid

Base Information

Chemical Name:2-Acryloylbenzoic acid
CAS No.:88238-55-5
Molecular Formula:C10H8O3
Molecular Weight:176.172
Hs Code.:
DSSTox Substance ID:DTXSID50600498
Wikidata:Q82496607

Synonyms:2-Acryloylbenzoic acid;88238-55-5;acryloylbenzoic acid;SCHEMBL14918787;DTXSID50600498

Suppliers and Price of 2-Acryloylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Acryloylbenzoic acid

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:176.047344113
Heavy Atom Count:13
Complexity:232

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CC(=O)C1=CC=CC=C1C(=O)O

Technology Process of 2-Acryloylbenzoic acid

There total 3 articles about 2-Acryloylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 88238-49-7
(Z)-3-(2-bromoethylidene)-phthalide

: 88238-55-5
3-(2-carboxyphenyl)-1-propen-3-one (vinyl ketone)

Guidance literature:: With hydrogenchloride; sodium hydrogencarbonate; In acetone; for 0.5h; Ambient temperature;
DOI:10.1248/cpb.31.2698

Reference yield:

: 74221-76-4,88270-98-8
ampicillin (3-phthalidylidene)ethyl ester hydrochloride

: 88238-55-5
3-(2-carboxyphenyl)-1-propen-3-one (vinyl ketone)

: 5187-94-0,7177-48-2,32388-53-7,57095-77-9,145454-26-8
ampicillin trihydrate

Guidance literature:: With sodium hydrogencarbonate; at 37 ℃; studiing because of the similarity to in vivo hydrolysis;
DOI:10.1248/cpb.31.2698

Reference yield:

: 61658-90-0
3-ethylidenephthalide

: 88238-55-5
3-(2-carboxyphenyl)-1-propen-3-one (vinyl ketone)

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / N-bromosuccinimide, α,α'-azobisisobutyronitrile / CCl4 / 20 h / Heating

2: 50 percent / sat. aq. sodium bicarbonate, 2N HCl / acetone / 0.5 h / Ambient temperature

With hydrogenchloride; N-Bromosuccinimide; azobisisobutyronitrile; sodium hydrogencarbonate; In tetrachloromethane; acetone;
DOI:10.1248/cpb.31.2698