2-((1H-imidazol-2-yl)thio)-5-fluoroaniline

Base Information

Chemical Name:2-((1H-imidazol-2-yl)thio)-5-fluoroaniline
CAS No.:88251-70-1
Molecular Formula:C9H8FN3S
Molecular Weight:209.247
Hs Code.:
DSSTox Substance ID:DTXSID10528381
Wikidata:Q82397973

Synonyms:88251-70-1;2-((1H-imidazol-2-yl)thio)-5-fluoroaniline;DTXSID10528381;5-Fluoro-2-[(1H-imidazol-2-yl)sulfanyl]aniline

Suppliers and Price of 2-((1H-imidazol-2-yl)thio)-5-fluoroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-((1H-imidazol-2-yl)thio)-5-fluoroaniline

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:209.04229660
Heavy Atom Count:14
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)N)SC2=NC=CN2

Technology Process of 2-((1H-imidazol-2-yl)thio)-5-fluoroaniline

There total 2 articles about 2-((1H-imidazol-2-yl)thio)-5-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 88251-65-4
2-(4-fluoro-2-nitrophenylthio)imidazole

: 88251-70-1
2-(2-amino-4-fluorophenylthio)imidazole

Guidance literature:: With hydrogenchloride; iron; In ethanol; for 2h; Heating;
DOI:10.1002/jhet.5570200528

Reference yield:

: 364-74-9
1,4-difluoro-2-nitrobenzene

: 88251-70-1
2-(2-amino-4-fluorophenylthio)imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / NaOC₂H₅ / ethanol / 4 h / Heating

2: 84 percent / iron powder, hydrochloric acid / aq. ethanol / 2 h / Heating

With hydrogenchloride; sodium ethanolate; iron; In ethanol;
DOI:10.1002/jhet.5570200528