1-(Phenoxyethynyl)cyclohexan-1-ol

Base Information

Chemical Name:1-(Phenoxyethynyl)cyclohexan-1-ol
CAS No.:88297-91-0
Molecular Formula:C14H16O2
Molecular Weight:216.28
Hs Code.:
DSSTox Substance ID:DTXSID60522778
Wikidata:Q82388357

Synonyms:88297-91-0;1-(Phenoxyethynyl)cyclohexan-1-ol;DTXSID60522778

Suppliers and Price of 1-(Phenoxyethynyl)cyclohexan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(Phenoxyethynyl)cyclohexan-1-ol

Chemical Property:

Melting Point:43.5-44 °C(Solv: ligroine (8032-32-4))
Boiling Point:135-138 °C(Press: 0.2 Torr)
PSA：29.46000
Density:1.13±0.1 g/cm3(Predicted)
LogP:2.72150
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:216.115029749
Heavy Atom Count:16
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)(C#COC2=CC=CC=C2)O

Technology Process of 1-(Phenoxyethynyl)cyclohexan-1-ol

There total 5 articles about 1-(Phenoxyethynyl)cyclohexan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 89894-42-8
1,2-dichlorovinyl phenyl ether

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 88297-91-0
1-(phenoxyethynyl)cyclohexanol

Guidance literature:: 1,2-dichlorovinyl phenyl ether; With n-butyllithium; In diethyl ether; hexane; at -78 - -20 ℃; for 2h;

cyclohexanone; In diethyl ether; hexane; at -78 - 20 ℃;
DOI:10.1021/ol502224s

Reference yield:

: 108-95-2,27073-41-2
phenol

: 88297-91-0
1-(phenoxyethynyl)cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / dimethyl sulfoxide / 2 h / 20 °C

1.2: 4 h / 20 °C

2.1: n-butyllithium / hexane; diethyl ether / 2 h / -78 - -20 °C

2.2: -78 - 20 °C

With n-butyllithium; sodium hydroxide; In diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1021/ol502224s