4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide

Base Information

Chemical Name:4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide
CAS No.:88323-95-9
Molecular Formula:C₁₃H₁₅N₃O₃S₂
Molecular Weight:325.412
Hs Code.:
DSSTox Substance ID:DTXSID10523659
Wikidata:Q82389905

Synonyms:88323-95-9;DTXSID10523659;4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide

Suppliers and Price of 4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide

Chemical Property:

PSA：138.77000
LogP:4.20760
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:325.05548370
Heavy Atom Count:21
Complexity:491

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)NC2=NC(=C(S2)C(=O)C)C)S(=O)(=O)N

Technology Process of 4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide

There total 1 articles about 4-[(5-Acetyl-4-methyl-1,3-thiazol-2-yl)amino]-2-methylbenzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 66121-79-7
3-Methyl-4-sulphamylphenylthiourea

: 1694-29-7
3-chloropentane-2,4-dione

: 88323-95-9
4-(5-Acetyl-4-methyl-thiazol-2-ylamino)-2-methyl-benzenesulfonamide

Guidance literature:: In ethanol; Heating;

Reference yield:

: 88323-95-9
4-(5-Acetyl-4-methyl-thiazol-2-ylamino)-2-methyl-benzenesulfonamide

: 88324-10-1
4-(5-{1-[(E)-Hydroxyimino]-ethyl}-4-methyl-thiazol-2-ylamino)-2-methyl-benzenesulfonamide

Guidance literature:: With hydroxylamine hydrochloride; In pyridine; Ambient temperature;

Reference yield:

: 88323-95-9
4-(5-Acetyl-4-methyl-thiazol-2-ylamino)-2-methyl-benzenesulfonamide

: 88324-26-9
4-(3-Hydroxy-2,4'-dimethyl-4-oxo-2,3,4,5-tetrahydro-[2,5']bithiazolyl-2'-ylamino)-2-methyl-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: Hydroxylamine hydrochloride / pyridine / Ambient temperature

2: orthophosphoric acid / tetrahydrofuran / Ambient temperature

With phosphoric acid; hydroxylamine hydrochloride; In tetrahydrofuran; pyridine;