4-Morpholinecarboxylic acid, 5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2- dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)-

Base Information

Chemical Name:4-Morpholinecarboxylic acid, 5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2- dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)-
CAS No.:883441-25-6
Molecular Formula:C23H36ClFN2O5
Molecular Weight:475.001
Hs Code.:

4-Morpholinecarboxylic acid,
5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2-
dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Morpholinecarboxylic acid, 5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2- dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)-

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Technology Process of 4-Morpholinecarboxylic acid, 5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2- dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)-

There total 1 articles about 4-Morpholinecarboxylic acid, 5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2- dimethylpropoxy)-, 1,1-dimethylethyl ester, (2R,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 883441-24-5
(2R,5R)-5-[(1R,2S)-3-(3-chloro-5-fluorophenyl)-1-hydroxy-2-nitropropyl]-2-(2,2-dimethylpropoxy)-morpholine-4-carboxylic acid tert-butyl ester

: 883441-25-6
(2R,5R)-5-[(1S,2S)-2-amino-3-(3-chloro-5-fluorophenyl)-1-hydroxypropyl]-2-(2,2-dimethylpropoxy)-morpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: (2R,5R)-5-[(1R,2S)-3-(3-chloro-5-fluorophenyl)-1-hydroxy-2-nitropropyl]-2-(2,2-dimethylpropoxy)-morpholine-4-carboxylic acid tert-butyl ester; With sodium tetrahydroborate; nickel dichloride; In methanol; at 20 ℃; for 0.333333h;

With sodium hydroxide; In methanol; water;