N-Phthaloyl-D-glutamic acid

Base Information

Chemical Name:N-Phthaloyl-D-glutamic acid
CAS No.:22911-88-2
Molecular Formula:C13H11 N O6
Molecular Weight:277.233
Hs Code.:
UNII:51R2443PBA
Nikkaji Number:J231.866K
Wikidata:Q27260914
Mol file:22911-88-2.mol

Synonyms:N-Phthaloyl-D-glutamic acid;51R2443PBA;22911-88-2;Phthaloyl-D-glutamic acid;N-Phthalyl-D-glutamic acid;D-2-Phthalimidoglutamic acid;UNII-51R2443PBA;Glutamic acid, 2-phthalimido-, D-;SCHEMBL7285516;2-PHTHALIMIDO-D-GLUTARIC ACID;Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, (2R)-;2-PHTHALIMIDOGLUTARIC ACID, (+)-;Q27260914

Suppliers and Price of N-Phthaloyl-D-glutamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Phthaloyl-D-glutamic acid

Chemical Property:

Vapor Pressure:1.34E-11mmHg at 25°C
Boiling Point:519°Cat760mmHg
Flash Point:267.7°C
PSA：111.98000
Density:1.566g/cm³
LogP:0.53850
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:277.05863707
Heavy Atom Count:20
Complexity:436

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)C(CCC(=O)O)C(=O)O
Isomeric SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)[C@H](CCC(=O)O)C(=O)O

Technology Process of N-Phthaloyl-D-glutamic acid

There total 5 articles about N-Phthaloyl-D-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
D-Glutamic acid

: 22509-74-6
N-ethoxycarbonylphthalimide

: 22911-88-2,2301-52-2
(R)-2-phthalimidoglutaric acid

Guidance literature:: With sodium carbonate; In water; at 0 - 20 ℃;
DOI:10.1002/chem.201802921

Reference yield:

: 171513-90-9
(+)-1-Phthalimido-1,3-diphenylpropane

: 22911-88-2,2301-52-2
(R)-2-phthalimidoglutaric acid

Guidance literature:: With periodic acid; ruthenium trichloride; In tetrachloromethane; acetonitrile; at 30 - 35 ℃; for 18h;
DOI:10.1039/a606586d

Reference yield:

: 1074-82-4
potassium phtalimide

: 22911-88-2,2301-52-2
(R)-2-phthalimidoglutaric acid

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 3-C3H5)Cl>2, dppe / tetrahydrofuran / 19 h / 50 °C

2: 90 percent / H₂ / 5percent Pd-C / ethyl acetate / 18 h / 760 Torr / Ambient temperature

3: aq. H₅IO₆ / RuCl₃*3H₂O / CCl₄; acetonitrile / 18 h / 30 - 35 °C

With hydrogen; periodic acid; ruthenium trichloride; palladium on activated charcoal; bis(η3-allyl-μ-chloropalladium(II)); 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; tetrachloromethane; ethyl acetate; acetonitrile;
DOI:10.1039/a606586d