N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide

Base Information

Chemical Name:N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide
CAS No.:88352-94-7
Molecular Formula:C14H13NO3
Molecular Weight:243.262
Hs Code.:
DSSTox Substance ID:DTXSID80549008
Wikidata:Q82427872

Synonyms:88352-94-7;N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide;N-[2-(Furan-2-yl)-2-oxoethyl]-4-methylbenzamide;SCHEMBL10722950;DTXSID80549008;FHCIKSCEFONQSB-UHFFFAOYSA-N;N-(4-methylbenzoyl)-(2-furylcarbonyl)methylamine

Suppliers and Price of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:243.08954328
Heavy Atom Count:18
Complexity:308

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)NCC(=O)C2=CC=CO2

Technology Process of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide

There total 1 articles about N-(2-(Furan-2-yl)-2-oxoethyl)-4-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.3%

: 88352-86-7
(furan-2-ylcarbonyl)methylamine hydrochloride

: 874-60-2
4-methyl-benzoyl chloride

: 88352-94-7
N-(4-methylbenzoyl)-(furan-2-ylcarbonyl)methylamine

Guidance literature:: With sodium hydrogencarbonate; In water; ethyl acetate; Ambient temperature;
DOI:10.1021/jm00401a021

Reference yield:

: 88352-94-7
N-(4-methylbenzoyl)-(furan-2-ylcarbonyl)methylamine

: 88352-73-2
(5-Furan-2-yl-2-p-tolyl-oxazol-4-yl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / NaH / paraffin; dimethylformamide / 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min

2: 42 percent / phosphoryl chloride / dimethylformamide / 8 h / Ambient temperature

3: 56 percent / KOH / methanol; H₂O / 8 h / 50 °C

With potassium hydroxide; sodium hydride; trichlorophosphate; In methanol; water; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jm00401a021

Reference yield:

: 88352-94-7
N-(4-methylbenzoyl)-(furan-2-ylcarbonyl)methylamine

: 88352-56-1
ethyl 2-[2-(4-methylphenyl)-5-(2-furyl)-4-oxazolyl]acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / NaH / paraffin; dimethylformamide / 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min

2: 42 percent / phosphoryl chloride / dimethylformamide / 8 h / Ambient temperature

With sodium hydride; trichlorophosphate; In N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jm00401a021