2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-

Base Information

Chemical Name:2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-
CAS No.:88426-95-3
Molecular Formula:C17H17NO4S
Molecular Weight:331.392
Hs Code.:
DSSTox Substance ID:DTXSID00469759

Synonyms:88426-95-3;2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-;DTXSID00469759

Suppliers and Price of 2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:331.08782920
Heavy Atom Count:23
Complexity:519

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCCC2C3=CC=CC=C3NC2=O

Technology Process of 2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-

There total 3 articles about 2H-Indol-2-one, 1,3-dihydro-3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 3690-95-7
(+/-)-3-(2-hydroxy-ethyl)-1,3-dihydro-indol-2-one

: 98-59-9
p-toluenesulfonyl chloride

: 88426-95-3
3-[2-(tosyloxy)ethyl]-2-indolinone

Guidance literature:: With pyridine; at 20 ℃; for 3h;
DOI:10.1016/j.tet.2006.01.036

Reference yield: 53.9%

: 3690-95-7
(+/-)-3-(2-hydroxy-ethyl)-1,3-dihydro-indol-2-one

: 98-59-9
p-toluenesulfonyl chloride

: 88426-99-7
3-(2-Chloro-ethyl)-1,3-dihydro-indol-2-one

: 88426-95-3
3-[2-(tosyloxy)ethyl]-2-indolinone

: 13861-75-1
spiro[cyclopropane-1,3'-indolin]-2'-one

Guidance literature:: at 0 ℃; for 36h;

Reference yield:

: 526-55-6,930395-07-6
2-(3-indole)-ethanol

: 88426-95-3
3-[2-(tosyloxy)ethyl]-2-indolinone

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / HCl; dimethyl sulfoxide / H₂O / 6 h / 20 °C

2: 86 percent / pyridine / 3 h / 20 °C

With pyridine; hydrogenchloride; dimethyl sulfoxide; In water;
DOI:10.1016/j.tet.2006.01.036