2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one

Base Information

Chemical Name:2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one
CAS No.:884500-73-6
Molecular Formula:C₁₄H₉NO₃
Molecular Weight:239.23
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10469826
Wikidata:Q82297708
Mol file:884500-73-6.mol

Synonyms:2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one;884500-73-6;2-(4-hydroxyphenyl)pyrano[3,2-b]pyridin-4-one;SCHEMBL311223;DTXSID10469826;NHPGMWSXLJULOQ-UHFFFAOYSA-N;2-(4-hydroxy-phenyl)-pyrano[3,2-b]pyridin-4-one;2-(4-Hydroxyphenyl)-4H-pyrano[3,2-b]pyridin-4-one

Suppliers and Price of 2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-HYDROXYPHENYL)-PYRANO[3,2-B]PYRIDIN-4-ONE 95.00%
1G
$ 952.01

Total 3 raw suppliers

Chemical Property of 2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one

Chemical Property:

PSA：63.33000
LogP:2.56060
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:239.058243149
Heavy Atom Count:18
Complexity:358

Purity/Quality:

99% ^*data from raw suppliers

2-(4-HYDROXYPHENYL)-PYRANO[3,2-B]PYRIDIN-4-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=O)C=C(O2)C3=CC=C(C=C3)O)N=C1

Technology Process of 2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one

There total 4 articles about 2-(4-Hydroxyphenyl)-pyrano[3,2-b]pyridin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.2%

: 884501-76-2
1-(4-methoxyphenyl)-3-(3-methoxypyridin-2-yl)propane-1,3-dione

: 884500-73-6
2-(4-hydroxyphenyl)-4H-pyrano[3,2-b]pyridin-4-one

Guidance literature:: With hydrogen bromide; In water; for 3h; Heating / reflux;

Reference yield:

: 24059-83-4
3-methoxypyridine-2-carboxylic acid methyl ester

: 884500-73-6
2-(4-hydroxyphenyl)-4H-pyrano[3,2-b]pyridin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / Inert atmosphere

1.2: 20 °C

2.1: hydrogen bromide / water / 3 h / Reflux

2.2: pH 7

With hydrogen bromide; sodium hydride; In water; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 874-24-8
3-hydroxypyridine-2-carboxylic acid

: 884500-73-6
2-(4-hydroxyphenyl)-4H-pyrano[3,2-b]pyridin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / 24 h / 64 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / Inert atmosphere

3.2: 20 °C

4.1: hydrogen bromide / water / 3 h / Reflux

4.2: pH 7

With sulfuric acid; hydrogen bromide; sodium hydride; potassium carbonate; In water; N,N-dimethyl-formamide; mineral oil;