2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one

Base Information

Chemical Name:2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one
CAS No.:884500-75-8
Molecular Formula:C₁₄H₈FNO₃
Molecular Weight:257.221
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90470177
Wikidata:Q82298175
Mol file:884500-75-8.mol

Synonyms:884500-75-8;2-(3-fluoro-4-hydroxyphenyl)pyrano[2,3-b]pyridin-4-one;2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one;SCHEMBL311979;DTXSID90470177;2-(3-Fluoro-4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Suppliers and Price of 2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(3-FLUORO-4-HYDROXY-PHENYL)-PYRANO[2,3-B]PYRIDIN-4-ONE 95.00%
1G
$ 964.14

Total 2 raw suppliers

Chemical Property of 2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one

Chemical Property:

PSA：63.33000
LogP:2.69970
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:257.04882128
Heavy Atom Count:19
Complexity:398

Purity/Quality:

99% ^*data from raw suppliers

2-(3-FLUORO-4-HYDROXY-PHENYL)-PYRANO[2,3-B]PYRIDIN-4-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)F

Technology Process of 2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one

There total 4 articles about 2-(3-Fluoro-4-hydroxyphenyl)-pyrano[2,3-b]pyridin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 884501-78-4
1-(3-fluoro-4-methoxyphenyl)-3-(2-methoxypyridin-3-yl)propane-1,3-dione

: 884500-75-8
2-(3-fluoro-4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Guidance literature:: With pyridine hydrochloride; at 190 ℃; for 4h;

Reference yield: 59.0%

: C₁₅H₁₂FNO₄

: 884500-75-8
2-(3-fluoro-4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Guidance literature:: With pyridine hydrochloride; at 190 ℃; for 4h;

Reference yield:

: 1452-94-4
ethyl 2-chloronicotinate

: 884500-75-8
2-(3-fluoro-4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 16 h / Reflux

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h

3: pyridine hydrochloride / 4 h / 190 °C

With pyridine hydrochloride; sodium hydride; In N,N-dimethyl-formamide; mineral oil;