4-(Chloromethyl)-5-ethylfuran-2-carboxamide

Base Information

Chemical Name:4-(Chloromethyl)-5-ethylfuran-2-carboxamide
CAS No.:884588-32-3
Molecular Formula:C₈H₁₀ClNO₂
Molecular Weight:187.626
Hs Code.:
DSSTox Substance ID:DTXSID70364065
Wikidata:Q82147826

Synonyms:884588-32-3;4-(CHLOROMETHYL)-5-ETHYL-2-FURAMIDE;4-(chloromethyl)-5-ethylfuran-2-carboxamide;CHEMBRDG-BB 9071731;DTXSID70364065;MFCD05858887;AKOS006242427;BS-36040

Suppliers and Price of 4-(Chloromethyl)-5-ethylfuran-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Chloromethyl)-5-ethylfuran-2-carboxamide

Chemical Property:

Vapor Pressure:0.0138mmHg at 25°C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:187.0400063
Heavy Atom Count:12
Complexity:174

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(C=C(O1)C(=O)N)CCl

Technology Process of 4-(Chloromethyl)-5-ethylfuran-2-carboxamide

There total 5 articles about 4-(Chloromethyl)-5-ethylfuran-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 884588-29-8
4-chloromethyl-5-ethyl-furan-2-carbonyl chloride

: 884588-32-3
4-chloromethyl-5-ethyl-furan-2-carboxylic acid amide

Guidance literature:: With ammonium hydroxide; at 0 ℃; for 1h;
DOI:10.1007/s11176-005-0317-8

Reference yield:

: 71387-70-7
5-ethyl-furan-2-carboxylic acid methyl ester

: 884588-32-3
4-chloromethyl-5-ethyl-furan-2-carboxylic acid amide

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / ZnCl₂ / 1,2-dichloro-ethane / 30 - 33 °C

2: 82 percent / AcOH Ac₂O / 15 h / Heating

3: NaOH / H₂O / 6 h / Heating

4: 10.5 g / SOCl₂ / benzene / 4 h / Heating

5: 8.4 g / aq. ammonia / 1 h / 0 °C

With ammonium hydroxide; sodium hydroxide; thionyl chloride; acetic anhydride; acetic acid; zinc(II) chloride; In water; 1,2-dichloro-ethane; benzene;
DOI:10.1007/s11176-005-0317-8

Reference yield:

: 100378-79-8
4-hydroxymethyl-5-ethylfuran-2-carboxylic acid

: 884588-32-3
4-chloromethyl-5-ethyl-furan-2-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 10.5 g / SOCl₂ / benzene / 4 h / Heating

2: 8.4 g / aq. ammonia / 1 h / 0 °C

With ammonium hydroxide; thionyl chloride; In benzene;
DOI:10.1007/s11176-005-0317-8