2,5-DIMETHYL-1-P-TOLYL-1H-PYRROLE

Base Information

• Chemical Name: 2,5-DIMETHYL-1-P-TOLYL-1H-PYRROLE
• CAS No.: 5044-26-8
• Molecular Formula: C25H25N3
• Molecular Weight: 185.269
• Hs Code.: 2933990090
• Mol file: 5044-26-8.mol

Synonyms:p-Methyltrifluoroacetanilide;N-trifluoroacetyl-p-toluidine;p-Toluidine Trifluoroacetamide;2,2,2-trifluoro-N-p-tolylacetamide;2,2,2-trifluoro-4'-methylacetanilide;2,5-dimethyl-1-p-tolyl-pyrrole;

Chemical Property of 2,5-DIMETHYL-1-P-TOLYL-1H-PYRROLE

Chemical Property:

• Vapor Pressure: 7.92E-13mmHg at 25°C
• Boiling Point: 291°Cat760mmHg
• Flash Point: 129.8°C
• PSA: 4.93000
• Density: 0.96g/cm³
• LogP: 3.40250

Purity/Quality:

98%min ^*data from raw suppliers

2,5-Dimethyl-1-(p-tolyl)-pyrrole 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-DIMETHYL-1-P-TOLYL-1H-PYRROLE

There total 12 articles about 2,5-DIMETHYL-1-P-TOLYL-1H-PYRROLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-methyl-4-nitrobenzene (99-99-0) + 2,5-hexanedione (110-13-4) → 2,5-dimethyl-1-p-tolyl-1H-pyrrole (5044-26-8)

Guidance literature:

With formic acid; for 12h; Autoclave; Inert atmosphere; Green chemistry;

DOI:10.1039/c7nj01898c

Reference yield: 99.0%

p-toluidine (106-49-0,12221-03-3) + 2,5-hexanedione (110-13-4) → 2,5-dimethyl-1-p-tolyl-1H-pyrrole (5044-26-8)

Guidance literature:

With amberlite IR 120 acidic resin; at 20 ℃; for 0.333333h; Neat (no solvent);

DOI:10.1080/00397911.2010.540766

Reference yield: 99.0%

2,5-Dimethylpyrrole (625-84-3) + p-toluidine (106-49-0,12221-03-3) → 2,5-dimethyl-1-p-tolyl-1H-pyrrole (5044-26-8)

Guidance literature:

In various solvent(s); at 110 ℃; pH=3;

DOI:10.1055/s-2006-941559

upstream raw materials:

p-toluidine

2,5-hexanedione

2,5-Dimethylpyrrole

hexa-1,5-diyne

Downstream raw materials:

1-(2,5-dimethyl-1-(p-tolyl)-1H-pyrrol-3-yl)ethanone

2-(4-tolyl)-1,3,4,7-tetramethylisoindole

pyrrolo[3',4':5,6][1,4]diphosphorino[2,3-c]pyrrole-14,8-dibromo-2,4,6,8-tetrahydro-1,3,5,7-tetramethyl-2,6-bis(4-methylphenyl)

C₁₄H₁₅Cl₂N₂O₂P